HitPredict

Interactor 1: IGHM (P01871)
Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region BOT) (Ig mu chain C region GAL) (Ig mu chain C region OU)
Gene: IGHM

Interactor 2: EGFL8 (Q99944)
Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2)
Gene: EGFL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009986 - cell surface
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 293
+	Hs
		379704 IGHA1_HUMAN (21-242): 3.72e-18: 88.1: 23.01		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		379301 IGHG1_HUMAN (5-220): 1.72e-15: 80.1: 15.98		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		379389 IGHG2_HUMAN (7-220): 3.52e-14: 76.2: 15.21		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		86029 IGLL5_HUMAN (96-213): 3.77e-13: 70.2: 22.88		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		49209 IGLC7_HUMAN (107-212): 2.21e-12: 65.2: 25.47		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Dm
		663797 Q9GPP6_DROME (318-472): 2.51e-13: 74.7: 17.95		SLIT_DROME (103-292): 1.28e-23: 102: 14.78
+	Dm
		663801 Q9VPZ7_DROME (318-472): 2.32e-13: 74.7: 17.95		SLIT_DROME (103-292): 1.28e-23: 102: 14.78
+	Hs
		1366058 PXDN_HUMAN (2-108): 8.28e-12: 70: 14.02		NELL1_HUMAN (88-186): 3.46e-23: 101: 31.43
+	Hs
		379652 IGHA1_HUMAN (21-242): 3.72e-18: 88.1: 23.01		FBLN7_HUMAN (63-186): 1.68e-15: 77.9: 23.12
+	Dm
		233627 O44924_DROME (326-432): 1.53e-09: 62.7: 16.82		SLIT_DROME (103-292): 1.28e-23: 102: 14.78
+	Dm
		663803 Q9W213_DROME (326-432): 1.51e-09: 62.7: 16.82		SLIT_DROME (103-292): 1.28e-23: 102: 14.78
+	Hs
		1366065 PXDN_HUMAN (2-108): 8.28e-12: 70: 14.02		NELL2_HUMAN (95-186): 3.22e-19: 89.4: 29.59
+	Hs
		317597 ROBO1_HUMAN (327-432): 4.61e-09: 61.2: 13.89		SLIT2_HUMAN (109-291): 2.97e-21: 95.6: 15.08
+	Hs
		1398301 ROBO3_HUMAN (305-472): 7.14e-09: 60.4: 11.18		NELL2_HUMAN (95-186): 3.22e-19: 89.4: 29.59
+	Hs
		586209 IGLL1_HUMAN (107-212): 6.5e-12: 66.8: 22.64		FAT1_HUMAN (7-66): 1.92e-13: 72.9: 10.00
+	Hs
		1047673 PXDN_HUMAN (2-108): 8.28e-12: 70: 14.02		NOTC2_HUMAN (6-210): 1.58e-10: 64: 10.66