HitPredict

Interactor 1: IGHG1 (P01857)
Immunoglobulin heavy constant gamma 1 (Ig gamma-1 chain C region) (Ig gamma-1 chain C region EU) (Ig gamma-1 chain C region KOL) (Ig gamma-1 chain C region NIE)
Gene: IGHG1

Interactor 2: EGFL8 (Q99944)
Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2)
Gene: EGFL8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 399 Hs			1 293
+	Hs
		379389 IGHG2_HUMAN (1-399): 9.41e-104: 314: 90.48		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		379704 IGHA1_HUMAN (1-374): 2.08e-62: 207: 29.85		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		379652 IGHA1_HUMAN (1-374): 2.08e-62: 207: 29.85		FBLN7_HUMAN (63-186): 1.68e-15: 77.9: 23.12
+	Hs
		379566 IGHM_HUMAN (1-358): 8.89e-23: 101: 19.11		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		86029 IGLL5_HUMAN (2-103): 7.83e-12: 66.3: 31.43		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		49209 IGLC7_HUMAN (2-103): 5.56e-12: 63.6: 33.33		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		317597 ROBO1_HUMAN (4-267): 9e-23: 102: 13.86		SLIT2_HUMAN (109-291): 2.97e-21: 95.6: 15.08
+	Hs
		379132 IGKC_HUMAN (229-321): 1.53e-09: 57: 29.47		EGFL8_HUMAN (1-293): 1.15e-38: 139: 100.00
+	Hs
		1366058 PXDN_HUMAN (6-122): 7.3e-11: 66.2: 12.82		NELL1_HUMAN (88-186): 3.46e-23: 101: 31.43
+	Hs
		1366065 PXDN_HUMAN (6-122): 7.3e-11: 66.2: 12.82		NELL2_HUMAN (95-186): 3.22e-19: 89.4: 29.59
+	Hs
		586209 IGLL1_HUMAN (2-103): 1.05e-11: 65.9: 31.43		FAT1_HUMAN (7-66): 1.92e-13: 72.9: 10.00
+	Hs
		1047673 PXDN_HUMAN (6-122): 7.3e-11: 66.2: 12.82		NOTC2_HUMAN (6-210): 1.58e-10: 64: 10.66