Protein: EGFL8
Epidermal growth factor-like protein 8 (EGF-like protein 8) (Vascular endothelial statin-2) (VE-statin-2)

Gene: EGFL8
Organism: Homo sapiens
Interactions: 74
UniProt ID: Q99944

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0005102 - signaling receptor binding
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0009986 - cell surface

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1408265

EGFL7
Epidermal growth factor-like protein 7

4

18

High-throughput

0.892

High

425754

PERM
Myeloperoxidase

2

5

High-throughput

0.776

High

469829

CATG
Cathepsin G

2

20

High-throughput

0.776

High

664078

PRTN3
Myeloblastin

2

20

High-throughput

0.776

High

366203

HPT
Haptoglobin

1

17

High-throughput

0.691

High

1408264

DNJB9
DnaJ homolog subfamily B member 9

4

2

High-throughput

0.630

High

379038

PIGR
Polymeric immunoglobulin receptor

1

3

High-throughput

0.618

High

1408263

FBX28
F-box only protein 28

3

1

High-throughput

0.609

High

1408268

S4A7
Sodium bicarbonate cotransporter 3

3

6

High-throughput

0.609

High

1351337

BPIB1
BPI fold-containing family B member 1

2

2

High-throughput

0.601

High

469442

ELNE
Neutrophil elastase

1

20

High-throughput

0.575

High

654552

FBLN1
Fibulin-1

1

19

High-throughput

0.575

High

1098471

DNJC3
DnaJ homolog subfamily C member 3

1

8

High-throughput

0.575

High

1132132

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

19

High-throughput

0.575

High

361548

CERU
Ceruloplasmin

1

2

High-throughput

0.536

High

369389

A1AT
Alpha-1-antitrypsin

1

3

High-throughput

0.536

High

369499

AACT
Alpha-1-antichymotrypsin

1

2

High-throughput

0.536

High

369737

A2MG
Alpha-2-macroglobulin

1

3

High-throughput

0.536

High

369912

CO3
Complement C3

1

3

High-throughput

0.536

High

387316

APOA1
Apolipoprotein A-I

1

1

High-throughput

0.536

High

387881

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

4

High-throughput

0.536

High

390152

ALBU
Albumin

1

3

High-throughput

0.536

High

390301

VTDB
Vitamin D-binding protein

1

3

High-throughput

0.536

High

390944

TRFE
Serotransferrin

1

2

High-throughput

0.536

High

391079

TRFL
Lactotransferrin

1

2

High-throughput

0.536

High

391156

HEMO
Hemopexin

1

3

High-throughput

0.536

High

425231

IC1
Plasma protease C1 inhibitor

1

4

High-throughput

0.536

High

445057

S10A9
Protein S100-A9

1

2

High-throughput

0.536

High

535456

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.536

High

568172

PLSL
Plastin-2

1

7

High-throughput

0.536

High

575803

MMP9
Matrix metalloproteinase-9

1

12

High-throughput

0.536

High

602997

BPI
Bactericidal permeability-increasing protein

1

1

High-throughput

0.536

High

723955

LCN1
Lipocalin-1

1

4

High-throughput

0.536

High

833168

MNDA
Myeloid cell nuclear differentiation antigen

1

2

High-throughput

0.536

High

1009708

NGAL
Neutrophil gelatinase-associated lipocalin

1

4

High-throughput

0.536

High

1249432

OLFM4
Olfactomedin-4

1

6

High-throughput

0.536

High

361717

F13A
Coagulation factor XIII A chain

1

1

High-throughput

0.515

High

407774

VWF
von Willebrand factor

1

10

High-throughput

0.515

High

532897

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.515

High

698005

CALR
Calreticulin

1

9

High-throughput

0.515

High

389677

A1AG1
Alpha-1-acid glycoprotein 1

1

0

High-throughput

0.513

High

86029

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

7

High-throughput

0.489

High

1180084

SMTL2
Smoothelin-like protein 2

1

3

High-throughput

0.489

High

1225057

KANK2
KN motif and ankyrin repeat domain-containing protein 2

1

9

High-throughput

0.489

High

593787

PECA1
Platelet endothelial cell adhesion molecule

1

11

High-throughput

0.470

High

788165

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.470

High

1289879

Q86V38
Atrophin 1

1

9

High-throughput

0.470

High

1351869

NEK7
Serine/threonine-protein kinase Nek7

1

7

High-throughput

0.470

High

1360733

JPH3
Junctophilin-3

1

3

High-throughput

0.470

High

49209

IGLC7
Immunoglobulin lambda constant 7

1

7

High-throughput

0.445

High

379132

IGKC
Immunoglobulin kappa constant

1

8

High-throughput

0.445

High

379301

IGHG1
Immunoglobulin heavy constant gamma 1

1

12

High-throughput

0.445

High

379389

IGHG2
Immunoglobulin heavy constant gamma 2

1

15

High-throughput

0.445

High

379566

IGHM
Immunoglobulin heavy constant mu

1

16

High-throughput

0.445

High

379704

IGHA1
Immunoglobulin heavy constant alpha 1

1

13

High-throughput

0.445

High

709307

CCN2
CCN family member 2

1

6

High-throughput

0.445

High

963222

LYSC
Lysozyme C

1

3

High-throughput

0.445

High

1356086

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

6

High-throughput

0.445

High

1408262

BPIA1
BPI fold-containing family A member 1

1

1

High-throughput

0.445

High

949975

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.439

High

1387150

PAUF
Pancreatic adenocarcinoma up-regulated factor

1

0

High-throughput

0.426

High

1408259

LACRT
Extracellular glycoprotein lacritin

1

0

High-throughput

0.426

High

1154572

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.407

High

1277904

NUFP2
FMR1-interacting protein NUFIP2

1

4

High-throughput

0.407

High

1309240

KSR1
Kinase suppressor of Ras 1

1

9

High-throughput

0.407

High

1381578

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

2

High-throughput

0.407

High

1408261

MUC5B
Mucin-5B

1

20

High-throughput

0.407

High

1408260

LIME1
Lck-interacting transmembrane adapter 1

3

0

High-throughput

0.347

High

1408266

CCPG1
Cell cycle progression protein 1

3

0

High-throughput

0.339

High

1403764

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.282

High

1408267

TIM8B
Mitochondrial import inner membrane translocase subunit Tim8 B

1

0

High-throughput

0.282

High

474929

VIME
Vimentin

1

0

High-throughput

0.279

Low

384529

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.278

Low

1157305

PROL4
Proline-rich protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025