Interactor 1: VWF (P04275)
von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]
Gene: VWF

Interactor 2: ITB3 (P05106)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: ITGB3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 1694173, 30305279
Identification Methods solid phase assay, enzyme linked immunosorbent assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Integrin_B_tail~VWA
Common GO terms GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0007155 - cell adhesion
GO:0007596 - blood coagulation
GO:0030168 - platelet activation
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 2813
Hs

1 788
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024