HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: NAP1 (P25293)
Nucleosome assembly protein
Gene: NAP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	1.00	0.968

Property	Details
Experiments	12928440, 28468903, 31062022, 39601790, 11309407, 16554755, 16429126, 37968396, 22199229
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 417
+	Sc
		381414 H2B2_YEAST (1-131): 1.47e-45: 146: 96.95		NAP1_YEAST (1-417): 1.16e-129: 381: 100.00
+	Hs
		936763 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		NP1L1_HUMAN (23-416): 2.26e-115: 344: 31.75
+	Hs
		1163166 H2B2E_HUMAN (7-128): 3.7e-46: 147: 70.97		NP1L4_HUMAN (36-371): 4.48e-115: 343: 33.33
+	Hs
		754774 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		NP1L1_HUMAN (23-416): 2.26e-115: 344: 31.75
+	Hs
		936701 H2B1C_HUMAN (7-128): 6.83e-46: 146: 70.97		NP1L1_HUMAN (23-416): 2.26e-115: 344: 31.75
+	Hs
		449776 H2B1J_HUMAN (7-128): 5.8e-46: 146: 70.16		NP1L4_HUMAN (36-371): 4.48e-115: 343: 33.33
+	Hs
		754959 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		NP1L4_HUMAN (36-371): 4.48e-115: 343: 33.33
+	Hs
		936805 H2B3B_HUMAN (7-128): 2.31e-44: 143: 64.52		NP1L1_HUMAN (23-416): 2.26e-115: 344: 31.75
+	Hs
		1323963 H2B3B_HUMAN (7-128): 2.31e-44: 143: 64.52		NP1L4_HUMAN (36-371): 4.48e-115: 343: 33.33
+	Hs
		936830 H2B1A_HUMAN (29-128): 2.92e-32: 112: 80.00		NP1L1_HUMAN (23-416): 2.26e-115: 344: 31.75
+	Hs
		1381850 H2B1A_HUMAN (29-128): 2.92e-32: 112: 80.00		NP1L4_HUMAN (36-371): 4.48e-115: 343: 33.33
+	Dm
		380881 H2B_DROME (8-128): 2.22e-45: 145: 67.77		Q24150_DROME (43-365): 2.36e-96: 294: 28.66
+	Dm
		380894 H2B_DROME (8-128): 2.22e-45: 145: 67.77		Q9W1G7_DROME (43-365): 2.54e-96: 294: 28.66
+	Ce
		407229 H2B1_CAEEL (9-128): 2.34e-47: 150: 72.50		Q19007_CAEEL (69-387): 5.08e-85: 264: 29.23
+	Ce
		1166393 H2B2_CAEEL (8-128): 4.17e-47: 149: 71.90		Q19007_CAEEL (69-387): 5.08e-85: 264: 29.23
+	Hs
		754898 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		TSYL5_HUMAN (21-366): 1.03e-71: 232: 14.53
+	Hs
		754984 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		TSYL1_HUMAN (139-361): 6.2e-63: 210: 19.28
+	Hs
		946755 H2B1D_HUMAN (7-128): 2e-45: 145: 70.16		SET_HUMAN (133-361): 3.91e-58: 193: 20.96
+	Hs
		1029354 H2B1A_HUMAN (29-128): 2.92e-32: 112: 80.00		SET_HUMAN (133-361): 3.91e-58: 193: 20.96