HitPredict

Interactor 1: SET (Q01105)
Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I)
Gene: SET

Interactor 2: H2B1A (Q96A08)
Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)
Gene: H2BC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19358706
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0006337 - nucleosome disassembly and 1 others more... GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 290 Hs			1 127
+	Hs
		946755 SET_HUMAN (1-236): 1.98e-87: 264: 100.00		H2B1D_HUMAN (1-127): 1.38e-53: 166: 85.04
+	Hs
		754984 TSYL1_HUMAN (44-234): 1.34e-83: 259: 38.74		H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83
+	Hs
		1431859 TSYL2_HUMAN (34-283): 3.72e-76: 246: 31.20		U3KQK0_HUMAN (1-127): 1.53e-55: 172: 85.83
+	Hs
		754898 TSYL5_HUMAN (2-257): 1.22e-80: 251: 32.69		H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83
+	Hs
		1407997 TSYL2_HUMAN (34-283): 3.72e-76: 246: 31.20		H2B1N_HUMAN (1-127): 1.22e-53: 166: 85.83
+	Hs
		1163166 NP1L4_HUMAN (4-242): 2.1e-75: 236: 18.81		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		449776 NP1L4_HUMAN (4-242): 2.1e-75: 236: 18.81		H2B1J_HUMAN (1-127): 4.41e-54: 167: 85.04
+	Hs
		754959 NP1L4_HUMAN (4-242): 2.1e-75: 236: 18.81		H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83
+	Hs
		1030936 TSPY1_HUMAN (23-250): 1.5e-75: 234: 33.33		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		936763 NP1L1_HUMAN (2-278): 6.65e-74: 233: 18.41		H2B2E_HUMAN (1-127): 4.41e-54: 167: 85.83
+	Hs
		1381850 NP1L4_HUMAN (4-242): 2.1e-75: 236: 18.81		H2B1A_HUMAN (1-127): 1.73e-52: 163: 100.00
+	Hs
		754774 NP1L1_HUMAN (2-278): 6.65e-74: 233: 18.41		H2B1B_HUMAN (1-127): 6.9e-54: 166: 85.83
+	Hs
		936701 NP1L1_HUMAN (2-278): 6.65e-74: 233: 18.41		H2B1C_HUMAN (1-127): 8.23e-54: 166: 85.04
+	Hs
		936830 NP1L1_HUMAN (2-278): 6.65e-74: 233: 18.41		H2B1A_HUMAN (1-127): 1.73e-52: 163: 100.00
+	Hs
		1323963 NP1L4_HUMAN (4-242): 2.1e-75: 236: 18.81		H2B3B_HUMAN (1-127): 9.02e-51: 158: 85.83
+	Hs
		936805 NP1L1_HUMAN (2-278): 6.65e-74: 233: 18.41		H2B3B_HUMAN (1-127): 9.02e-51: 158: 85.83
+	Rn
		1026934 TSPY1_RAT (6-237): 1.63e-71: 225: 30.17		H2B1_RAT (1-127): 1.01e-50: 158: 81.89
+	Dm
		380881 Q24150_DROME (18-238): 4.15e-66: 212: 20.54		H2B_DROME (37-127): 3.49e-47: 149: 94.51
+	Dm
		380894 Q9W1G7_DROME (18-238): 3.69e-66: 212: 20.54		H2B_DROME (37-127): 3.49e-47: 149: 94.51
+	Sc
		381414 NAP1_YEAST (38-286): 1.23e-34: 131: 21.54		H2B2_YEAST (4-126): 4.48e-41: 134: 69.36