Interactor 1: P53 (P02340)
Cellular tumor antigen p53 (Tumor suppressor p53)
Gene: Tp53
Interactor 2: CBP (P45481)
Histone lysine acetyltransferase CREBBP (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: Crebbp
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9194565 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Creb_binding~P53_TAD, P53_TAD~zf-TAZ |
| Common GO terms | GO:0000785 - chromatin GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus and 9 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025