HitPredict

Interactor 1: HSP27 (P02518)
Heat shock protein 27
Gene: HSP27

Interactor 2: Q9VGI4 (Q9VGI4)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: Lk6

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 213 Dm			1 1142
+	Hs
		415557 HSPB1_HUMAN (4-198): 7.4e-59: 185: 27.78		KCC1A_HUMAN (109-403): 6.2e-112: 355: 32.43
+	Hs
		1110317 HSPB8_HUMAN (4-167): 2.22e-38: 133: 27.84		KCC2B_HUMAN (104-506): 5.91e-114: 370: 27.27
+	Hs
		415427 HSPB1_HUMAN (4-198): 7.4e-59: 185: 27.78		MAPK2_HUMAN (117-459): 2.2e-45: 171: 32.38
+	Mm
		572875 HSPB1_MOUSE (4-202): 1.04e-57: 183: 26.92		MAPK2_MOUSE (117-459): 6.85e-45: 169: 32.09
+	Hs
		415698 HSPB1_HUMAN (4-198): 7.4e-59: 185: 27.78		MAPK5_HUMAN (124-407): 1.15e-42: 164: 36.58
+	Mm
		572880 HSPB1_MOUSE (4-202): 1.04e-57: 183: 26.92		MAPK3_MOUSE (117-451): 5.49e-41: 157: 33.33
+	Hs
		415601 HSPB1_HUMAN (4-198): 7.4e-59: 185: 27.78		MAPK3_HUMAN (117-451): 4.64e-40: 154: 33.04
+	Hs
		1156304 HSPB2_HUMAN (4-164): 1.94e-37: 130: 27.95		MAPK5_HUMAN (124-407): 1.15e-42: 164: 36.58
+	Hs
		415445 HSPB1_HUMAN (4-198): 7.4e-59: 185: 27.78		KS6A3_HUMAN (79-394): 3.79e-19: 95.5: 29.54
+	Hs
		287641 CRYAA_HUMAN (16-194): 4.22e-48: 157: 25.97		KS6A5_HUMAN (122-443): 3.84e-21: 102: 29.34