HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MAGA2 (P43356)
Melanoma-associated antigen 2 (Cancer/testis antigen 1.2) (CT1.2) (MAGE-2 antigen)
Gene: MAGEA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 26468294, 16847267
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0016605 - PML body
GO:0031625 - ubiquitin protein ligase binding
GO:0042826 - histone deacetylase binding
and 2 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 393
Hs

1 314
+ Hs
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+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024