HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	38580884, 25471832, 33567341, 34141823, 19615732
Identification Methods	proximity labelling technology, affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 963
+	Hs
		387546 P53_HUMAN (1-393): 0: 619: 100.00		UBP29_HUMAN (270-954): 2.14e-83: 291: 17.67
+	Hs
		387242 P53_HUMAN (1-393): 0: 619: 100.00		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		387822 P53_HUMAN (1-393): 0: 619: 100.00		UBP3_HUMAN (464-933): 1.42e-51: 191: 17.94
+	Hs
		387699 P53_HUMAN (1-393): 0: 619: 100.00		UBP21_HUMAN (778-935): 1.96e-48: 183: 38.61
+	Hs
		387801 P53_HUMAN (1-393): 0: 619: 100.00		UBP15_HUMAN (485-644): 1.32e-17: 90.4: 10.18
+	Hs
		777076 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		UBP8_HUMAN (597-939): 3.73e-58: 219: 23.28