Interactor 1: RAF1 (P05625)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (C-MIL) (C-RAF) (MIL proto-oncogene serine/threonine-protein kinase) (RAF-1)
Gene: RAF1

Interactor 2: BRAF (Q04982)
Serine/threonine-protein kinase B-raf (EC 2.7.11.1) (Proto-oncogene B-Raf) (Proto-oncogene c-Rmil) (Serine/threonine-protein kinase Rmil)
Gene: BRAF

Species: Gallus gallus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27034005
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~PK_Tyr_Ser-Thr, C1_1~RBD, C1_1~Pkinase, PK_Tyr_Ser-Thr~Pkinase, RBD~RBD
Common GO terms GO:0000165 - MAPK cascade
GO:0004709 - MAP kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 647
Gg

1 766
+ Hs
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+ Xl
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+ At
+ Mm
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+ At
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Last updated: 15 Jul 2024