HitPredict

Interactor 1: HEPS (P05981)
Serine protease hepsin (EC 3.4.21.106) (Transmembrane protease serine 1) [Cleaved into: Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain]
Gene: HPN

Interactor 2: TOR2X (Q8N2E6)
Prosalusin (Torsin family 2 member A) (Torsin-2A) [Cleaved into: Salusin-alpha; Salusin-beta]
Gene: TOR2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 417 Hs			1 242
+	Hs
		151960 HEPS_HUMAN (1-417): 4.99e-176: 499: 100.00		TOR1A_HUMAN (6-197): 5.95e-79: 242: 43.23
+	Hs
		409523 HEPS_HUMAN (1-417): 4.99e-176: 499: 100.00		TOR2A_HUMAN (1-197): 2.59e-74: 230: 100.00
+	Hs
		409559 HEPS_HUMAN (1-417): 4.99e-176: 499: 100.00		TOR3A_HUMAN (10-197): 2.03e-65: 209: 37.11
+	Hs
		152037 TMPSD_HUMAN (29-411): 1.81e-125: 376: 34.46		TOR1A_HUMAN (6-197): 5.95e-79: 242: 43.23
+	Hs
		884426 TMPS3_HUMAN (27-406): 1.31e-132: 390: 35.94		TOR3A_HUMAN (10-197): 2.03e-65: 209: 37.11
+	Hs
		1316654 TMPSD_HUMAN (29-411): 1.81e-125: 376: 34.46		TOR3A_HUMAN (10-197): 2.03e-65: 209: 37.11
+	Hs
		1330327 TMPS5_HUMAN (11-403): 2.43e-126: 374: 33.08		TOR3A_HUMAN (10-197): 2.03e-65: 209: 37.11
+	Hs
		371472 KLKB1_HUMAN (90-416): 1.17e-95: 301: 31.85		TOR3A_HUMAN (10-197): 2.03e-65: 209: 37.11
+	Hs
		1231544 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR2X_HUMAN (1-242): 2.11e-96: 283: 100.00
+	Hs
		152058 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR1A_HUMAN (6-197): 5.95e-79: 242: 43.23
+	Hs
		1128311 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR2A_HUMAN (1-197): 2.59e-74: 230: 100.00
+	Hs
		1330730 ST14_HUMAN (152-400): 2.45e-50: 183: 40.70		TOR3A_HUMAN (10-197): 2.03e-65: 209: 37.11