HitPredict

Interactor 1: HLAA (P04439)
HLA class I histocompatibility antigen, A alpha chain (Human leukocyte antigen A) (HLA-A)
Gene: HLA-A

Interactor 2: CLC4A (Q9UMR7)
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367)
Gene: CLEC4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	C1-set~Lectin_C, Lectin_C~MHC_I
Common GO terms	GO:0005886 - plasma membrane GO:0009897 - external side of plasma membrane GO:0036037 - CD8-positive, alpha-beta T cell activation GO:0042590 - antigen processing and presentation of exogenous peptide antigen via MHC class I
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 365 Hs			1 237
+	Hs
		409536 HLAA_HUMAN (1-365): 2.04e-180: 506: 100.00		CLC4E_HUMAN (25-236): 1.45e-57: 183: 34.58
+	Hs
		409463 HLAA_HUMAN (1-365): 2.04e-180: 506: 100.00		CLC4D_HUMAN (31-237): 5.8e-55: 176: 33.33
+	Hs
		521048 HLAC_HUMAN (1-364): 5.11e-153: 436: 80.27		CLC4A_HUMAN (1-237): 2.21e-69: 214: 100.00
+	Hs
		380188 HLAB_HUMAN (1-362): 3.11e-160: 454: 85.64		CLC4E_HUMAN (25-236): 1.45e-57: 183: 34.58
+	Hs
		719760 HLAF_HUMAN (4-348): 8.58e-144: 412: 80.29		CLC4A_HUMAN (1-237): 2.21e-69: 214: 100.00
+	Hs
		521046 HLAC_HUMAN (1-364): 5.11e-153: 436: 80.27		CLC4E_HUMAN (25-236): 1.45e-57: 183: 34.58
+	Hs
		520942 HLAC_HUMAN (1-364): 5.11e-153: 436: 80.27		CLC4D_HUMAN (31-237): 5.8e-55: 176: 33.33
+	Hs
		379884 HLAB_HUMAN (1-362): 3.11e-160: 454: 85.64		NKG2A_HUMAN (2-233): 7.39e-41: 141: 16.38
+	Hs
		719759 HLAF_HUMAN (4-348): 8.58e-144: 412: 80.29		CLC4E_HUMAN (25-236): 1.45e-57: 183: 34.58
+	Hs
		607347 HLAG_HUMAN (1-338): 1.42e-154: 439: 82.84		NKG2A_HUMAN (2-233): 7.39e-41: 141: 16.38
+	Hs
		520892 HLAC_HUMAN (1-364): 5.11e-153: 436: 80.27		CLC4G_HUMAN (70-232): 1.02e-39: 140: 27.22
+	Hs
		719719 HLAF_HUMAN (4-348): 8.58e-144: 412: 80.29		CL12B_HUMAN (1-232): 4.37e-44: 151: 17.82
+	Hs
		568036 HLAE_HUMAN (20-357): 8.37e-146: 418: 78.99		NKG2A_HUMAN (2-233): 7.39e-41: 141: 16.38
+	Hs
		1376970 HMR1_HUMAN (1-348): 2.96e-112: 332: 36.29		CLC4E_HUMAN (25-236): 1.45e-57: 183: 34.58
+	Hs
		607425 HLAG_HUMAN (1-338): 1.42e-154: 439: 82.84		MRC2_HUMAN (118-230): 3.87e-11: 64.4: 22.61
+	Hs
		688605 HMR1_HUMAN (1-348): 2.96e-112: 332: 36.29		NKG2A_HUMAN (2-233): 7.39e-41: 141: 16.38