HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: NISCH (Q9Y2I1)
Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein)
Gene: NISCH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 1504
+	Hs
		434090 LYN_HUMAN (1-509): 0: 582: 62.72		NISCH_HUMAN (1-1504): 0: 1812: 100.00
+	Hs
		433876 LYN_HUMAN (1-509): 0: 582: 62.72		CEP97_HUMAN (221-554): 1.17e-54: 209: 25.85
+	Hs
		411718 LCK_HUMAN (1-509): 0: 661: 100.00		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01
+	Hs
		411699 LCK_HUMAN (1-509): 0: 661: 100.00		FLII_HUMAN (198-387): 6.39e-13: 76.3: 17.81
+	Hs
		433978 LYN_HUMAN (1-509): 0: 582: 62.72		LRRC1_HUMAN (202-471): 1.35e-19: 96.3: 21.22
+	Hs
		433758 LYN_HUMAN (1-509): 0: 582: 62.72		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01