Interactor 1: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Interactor 2: RB (P06400)
Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)
Gene: RB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.876

The method score is based on:

Property Details
Experiments 8288605, 8943373, 16360038
Identification Methods pull down, affinity chromatography technology, unspecified method, isothermal titration calorimetry, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DUF3452~RB_A, DUF3452~RB_B, RB_A~RB_A, RB_A~RB_B, RB_B~Rb_C
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0001894 - tissue homeostasis
and 74 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 928
Hs

1 928
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024