HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

The method score is based on:

Property	Details
Experiments	16621797, 36300783, 23383273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005654 - nucleoplasm and 13 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016887 - ATP hydrolysis activity GO:0019903 - protein phosphatase binding GO:0031625 - ubiquitin protein ligase binding GO:0032991 - protein-containing complex GO:0034605 - cellular response to heat GO:0034774 - secretory granule lumen GO:0042981 - regulation of apoptotic process GO:0045732 - positive regulation of protein catabolic process GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1	732
Hs

1	806

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024