Interactor 1: IL6 (P08505)
Interleukin-6 (IL-6) (B-cell hybridoma growth factor) (Interleukin HP-1)
Gene: IL6

Interactor 2: TF65 (Q04207)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: Rela

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.751

The method score is based on:

Property Details
Experiments 16166627, 16931600, 15536134, 15241416, 17982049, 19285436, 16413922, 20221401, 20534538, 21098092, 21131967
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0008284 - positive regulation of cell population proliferation
GO:0035729 - cellular response to hepatocyte growth factor stimulus
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0071222 - cellular response to lipopolysaccharide
and 1 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 211
Mm

1 549
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024