Interactor 1: RPB2 (P08518)
DNA-directed RNA polymerase II subunit RPB2 (RNA polymerase II subunit 2) (EC 2.7.7.6) (B150) (DNA-directed RNA polymerase II 140 kDa polypeptide)
Gene: RPB2

Interactor 2: RPAB1 (P20434)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (ABC27) (DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide)
Gene: RPB5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 10777588, 16429126, 37968396, 16554755, 18467557, 14759368, 20094031, 21386817, 22056778
Identification Methods biochemical, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction, anti tag coimmunoprecipitation, tandem affinity purification, ion exchange chromatography, cross-linking study, molecular sieving, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001055 - RNA polymerase II activity
GO:0001172 - RNA-templated transcription
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005665 - RNA polymerase II, core complex
and 3 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1224
Sc

1 215
+ Hs
+ Sp
+ Hs
+ Sc
+ Pf
+ Hs
+ Sc
+ Hv
+ Hv

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Last updated: 15 Jul 2024