HitPredict

Interactor 1: RASK (P08644)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: Kras

Interactor 2: CDK4 (P35426)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11384971
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044877 - protein-containing complex binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 189 Rn			1 303
+	Hs
		349133 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		CDK2_HUMAN (3-301): 4.1e-147: 416: 43.56
+	Rn
		442950 RASK_RAT (1-189): 2.66e-78: 233: 100.00		Q6P751_RAT (3-301): 1.17e-146: 415: 43.23
+	Hs
		625461 RB11B_HUMAN (4-176): 5.49e-73: 221: 34.29		CDK2_HUMAN (3-301): 4.1e-147: 416: 43.56
+	Hs
		349093 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		CDK4_HUMAN (1-303): 3.41e-130: 373: 95.05
+	Hs
		348617 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		CDK5_HUMAN (3-301): 5.56e-126: 362: 43.75
+	Hs
		349801 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		CDK1_HUMAN (3-299): 1.8e-131: 377: 42.38
+	Hs
		625297 RRAS2_HUMAN (3-188): 1.47e-54: 173: 54.12		CDK2_HUMAN (3-301): 4.1e-147: 416: 43.56