HitPredict

Interactor 1: RAP1 (P08645)
Ras-related protein Rap1 (EC 3.6.5.2) (Rap1 GTPase) (Ras-like protein 3)
Gene: RAP1

Interactor 2: Q8IPP3 (Q8IPP3)
Canoe, isoform D
Gene: cno

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.825

Property	Details
Experiments	14504224, 17846121, 15710747
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	DIL~Ras, PDZ~Ras, RA~Ras
Common GO terms	GO:0007391 - dorsal closure
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Dm			1 1817
+	Dm
		442967 RAP1_DROME (1-184): 7.38e-88: 257: 100.00		Q95TT5_DROME (1-1320): 0: 919: 85.83
+	Hs
		876348 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		AFAD_HUMAN (1-1703): 0: 776: 32.18
+	Hs
		914453 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5B_HUMAN (42-969): 1.49e-146: 500: 13.65
+	Hs
		1079976 RB11B_HUMAN (4-176): 1.4e-73: 222: 29.89		MYO5B_HUMAN (42-969): 1.49e-146: 500: 13.65
+	Hs
		914486 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5A_HUMAN (82-962): 5.37e-144: 493: 13.04
+	Rn
		914521 RB11A_RAT (4-179): 6.45e-75: 225: 28.81		MYO5B_RAT (77-969): 2.39e-141: 485: 13.96
+	Hs
		914383 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5C_HUMAN (79-961): 7.94e-123: 429: 12.79
+	Dm
		442954 RAP1_DROME (1-184): 7.38e-88: 257: 100.00		Q24279_DROME (654-1320): 1.18e-99: 359: 70.92
+	Dm
		51909 O18335_DROME (4-176): 6.54e-75: 225: 31.03		A1Z6Z9_DROME (82-928): 1.57e-98: 355: 12.21
+	Hs
		919668 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		RADIL_HUMAN (235-990): 9.28e-78: 283: 14.41
+	At
		1338479 RABD1_ARATH (4-179): 3.49e-73: 220: 31.64		MYO6_ARATH (215-955): 5.99e-77: 285: 10.36
+	Zm
		14343 B4FNJ6_MAIZE (4-178): 3.84e-73: 221: 34.46		A0A1D6G388_MAIZE (67-969): 4.61e-75: 280: 12.92
+	Hs
		914382 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI13B_HUMAN (189-705): 1.02e-63: 243: 14.95
+	Hs
		914346 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI13A_HUMAN (249-705): 1.61e-61: 236: 16.09
+	Mm
		918987 RAB1A_MOUSE (4-170): 5.46e-76: 228: 34.52		NEB2_MOUSE (995-1109): 2.67e-30: 132: 37.82
+	Mm
		895596 RAB8B_MOUSE (4-180): 8.19e-73: 219: 33.15		NEB2_MOUSE (995-1109): 2.67e-30: 132: 37.82
+	Hs
		895319 RAB2A_HUMAN (4-170): 1.54e-72: 219: 38.10		NEB1_HUMAN (995-1109): 2.59e-29: 129: 36.98
+	Hs
		914039 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		DLG1_HUMAN (890-1103): 2.52e-25: 116: 18.81
+	Hs
		895057 RAB2A_HUMAN (4-170): 1.54e-72: 219: 38.10		DLG1_HUMAN (890-1103): 2.52e-25: 116: 18.81
+	Hs
		914066 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		SCRIB_HUMAN (1010-1249): 6e-21: 103: 20.87