HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: SEPT8 (Q92599)
Septin-8
Gene: SEPTIN8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	20348541
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 595 Hs			1 483
+	Hs
		397045 ESR1_HUMAN (1-595): 0: 599: 100.00		SEP11_HUMAN (11-402): 0: 546: 81.12
+	Hs
		396795 ESR1_HUMAN (1-595): 0: 599: 100.00		SEPT5_HUMAN (1-383): 8.98e-172: 489: 36.99
+	Hs
		396134 ESR1_HUMAN (1-595): 0: 599: 100.00		SEPT2_HUMAN (9-353): 1.01e-162: 466: 38.98
+	Hs
		397151 ESR1_HUMAN (1-595): 0: 599: 100.00		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40
+	Hs
		1156400 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		SEPT7_HUMAN (2-427): 0: 547: 40.83
+	Hs
		1367395 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		SEP11_HUMAN (11-402): 0: 546: 81.12
+	Hs
		404049 GCR_HUMAN (5-557): 4.69e-109: 346: 22.51		SEPT6_HUMAN (1-429): 0: 580: 76.22
+	Hs
		1136991 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		SEPT2_HUMAN (9-353): 1.01e-162: 466: 38.98
+	Hs
		1367518 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81
+	Hs
		210484 NR4A1_HUMAN (64-549): 2.82e-105: 331: 24.54		SEPT4_HUMAN (2-382): 1.87e-174: 500: 36.67
+	Hs
		442944 PRGR_HUMAN (183-508): 6.95e-44: 170: 32.14		SEPT7_HUMAN (2-427): 0: 547: 40.83
+	Hs
		442960 PRGR_HUMAN (183-508): 6.95e-44: 170: 32.14		SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81