HitPredict

Interactor 1: H2AV (P08985)
Histone H2A.v (H2A.F/Z) (H2A.Z)
Gene: His2Av

Interactor 2: PARP (P35875)
Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.30) (NAD(+) ADP-ribosyltransferase) (ADPRT) (Poly[ADP-ribose] synthase) (Protein ADP-ribosyltransferase Parp) (EC 2.4.2.-)
Gene: PARP

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	31028139, 17827147
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000791 - euchromatin GO:0005694 - chromosome GO:0005700 - polytene chromosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 141 Dm			1 994
+	Hs
		555678 H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04		PARP2_HUMAN (439-992): 0: 627: 36.51
+	Hs
		1151393 H2A2A_HUMAN (5-132): 1.71e-59: 181: 61.24		PARP2_HUMAN (439-992): 0: 627: 36.51
+	Hs
		391953 H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47		PARP2_HUMAN (439-992): 0: 627: 36.51
+	Hs
		470194 H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36		PARP2_HUMAN (439-992): 0: 627: 36.51
+	Hs
		470599 H2A1_HUMAN (5-132): 2.4e-59: 181: 60.47		PARP2_HUMAN (439-992): 0: 627: 36.51
+	Hs
		470039 H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36		PAR14_HUMAN (754-989): 4.32e-34: 144: 14.23
+	Hs
		555353 H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04		DNLI3_HUMAN (4-107): 1.92e-28: 125: 21.05
+	Hs
		391601 H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47		DNLI3_HUMAN (4-107): 1.92e-28: 125: 21.05
+	Hs
		469968 H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36		DNLI3_HUMAN (4-107): 1.92e-28: 125: 21.05
+	Hs
		470301 H2A1_HUMAN (5-132): 2.4e-59: 181: 60.47		DNLI3_HUMAN (4-107): 1.92e-28: 125: 21.05
+	Hs
		555522 H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04		ZCCHV_HUMAN (632-988): 9.55e-26: 116: 13.86
+	Hs
		470434 H2A1_HUMAN (5-132): 2.4e-59: 181: 60.47		ZCCHV_HUMAN (632-988): 9.55e-26: 116: 13.86
+	Hs
		455054 H2AX_HUMAN (5-141): 6.11e-60: 183: 57.04		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74
+	Hs
		391516 H2A1B_HUMAN (5-132): 3.12e-59: 181: 60.47		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74
+	Hs
		455011 H2AZ_HUMAN (1-122): 1.5e-59: 181: 98.36		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74
+	Hs
		455012 H2A1_HUMAN (5-132): 2.4e-59: 181: 60.47		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74
+	Hs
		455554 H2A2A_HUMAN (5-132): 1.71e-59: 181: 61.24		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74
+	Hs
		455732 H2A1C_HUMAN (5-132): 1.83e-59: 181: 60.47		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74
+	Hs
		455802 H2A1J_HUMAN (5-130): 2.43e-59: 181: 60.63		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74
+	Hs
		455622 H2A2B_HUMAN (5-132): 8.46e-59: 179: 59.69		PARP1_HUMAN (103-513): 4.94e-19: 94.9: 15.74