HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007015 - actin filament organization
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 236
+	Hs
		418991 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		1137877 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		418937 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		932019 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		RHOU_HUMAN (32-236): 2.81e-89: 265: 60.48
+	Hs
		419027 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		951069 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		931991 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		RHOG_HUMAN (31-210): 1.12e-78: 236: 49.44
+	Hs
		451225 TPM1_HUMAN (1-284): 2.35e-44: 153: 100.00		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		1137895 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		925344 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		932039 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		RHOV_HUMAN (1-236): 3.37e-76: 231: 100.00
+	Hs
		925177 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		RAC1_HUMAN (32-217): 3.34e-76: 230: 53.23
+	Hs
		892423 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RAC3_HUMAN (32-206): 6.17e-74: 224: 56.00
+	Hs
		564564 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RHOQ_HUMAN (23-236): 1.99e-73: 223: 50.00
+	Hs
		545430 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RAC2_HUMAN (32-216): 6.11e-73: 222: 52.43
+	Hs
		900570 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RHOA_HUMAN (33-215): 9.31e-73: 221: 42.62
+	Hs
		894116 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		CDC42_HUMAN (32-207): 2.12e-66: 205: 57.39
+	Hs
		1137905 MRCKA_HUMAN (1-282): 1.08e-31: 126: 17.67		RHOJ_HUMAN (32-214): 8.3e-59: 186: 50.27