Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1
Interactor 2: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26151834, 16169070, 25253489, 31839598, 21360678, 12853476, 8289821, 21460846, 25036637 |
| Identification Methods | pull down, two hybrid, cross-linking study, affinity chromatography technology, molecular sieving, blue native page, anti tag coimmunoprecipitation, two hybrid pooling approach, luminescence based mammalian interactome mapping |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HATPase_c_3~HATPase_c_3, HATPase_c_3~HSP90, HSP90~HSP90 |
| Common GO terms | GO:0001764 - neuron migration GO:0002134 - UTP binding GO:0002135 - CTP binding GO:0002218 - activation of innate immune response GO:0002230 - positive regulation of defense response to virus by host and 89 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025