Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1
Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.960 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10543959, 25253489, 39366960, 31839598, 21183720, 30382094, 22939624 |
| Identification Methods | pull down, cross-linking study, fluorescent resonance energy transfer, mass spectrometry studies of complexes, x ray scattering, molecular sieving, luminescence based mammalian interactome mapping |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HATPase_c_3~HATPase_c_3, HATPase_c_3~HSP90, HSP90~HSP90 |
| Common GO terms | GO:0001890 - placenta development GO:0003723 - RNA binding GO:0003725 - double-stranded RNA binding GO:0005524 - ATP binding GO:0005576 - extracellular region and 65 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025