HitPredict

Interactor 1: PBS2 (P08018)
MAP kinase kinase PBS2 (EC 2.7.12.2) (Polymyxin B resistance protein 2) (Suppressor of fluoride sensitivity 4)
Gene: PBS2

Interactor 2: SSK22 (P25390)
Serine/threonine-protein kinase SSK22 (EC 2.7.11.1) (MAP kinase kinase kinase SSK22) (Suppressor of sensor kinase 22)
Gene: SSK22

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.831

The method score is based on:

Property Details
Experiments 12853477, 20489023
Identification Methods two hybrid, affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0038066 - p38MAPK cascade
GO:0106310 - protein serine kinase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 668
Sc

1 1331
+ Sc
+ Sp
+ Sp
+ Hs
+ Hs
+ At
+ At
+ At
+ At
+ Hs
+ Sc
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025