Protein: STE11
Serine/threonine-protein kinase STE11 (EC 2.7.11.25)

Gene: STE11
Organism: Saccharomyces cerevisiae S288C
Interactions: 67
UniProt ID: P23561

Gene Ontology (top 5):
GO:0000196 - cell integrity MAPK cascade
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001402 - signal transduction involved in filamentous growth
GO:0001403 - invasive growth in response to glucose limitation
GO:0004672 - protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

660307

STE11
Serine/threonine-protein kinase STE11

14

14

Small-scale

0.978

High

599327

FUS3
Mitogen-activated protein kinase FUS3

7

16

Small-scale

0.953

High

660318

STE5
Protein STE5

18

0

Small-scale

0.937

High

392263

HSP82
ATP-dependent molecular chaperone HSP82

5

20

Small-scale

0.927

High

464556

PBS2
MAP kinase kinase PBS2

5

19

Small-scale

0.925

High

574637

KSS1
Mitogen-activated protein kinase KSS1

5

20

Small-scale

0.920

High

448852

STE7
Serine/threonine-protein kinase STE7

5

15

Small-scale

0.914

High

438186

CDC37
Hsp90 co-chaperone Cdc37

4

9

Small-scale

0.882

High

578882

HSC82
ATP-dependent molecular chaperone HSC82

3

20

Small-scale

0.847

High

660340

STE20
Serine/threonine-protein kinase STE20

3

18

Small-scale

0.845

High

660309

MAS5
Mitochondrial protein import protein MAS5

3

12

Small-scale

0.827

High

660308

STE50
Protein STE50

27

1

Small-scale

0.769

High

660316

MKK1
MAP kinase kinase MKK1/SSP32

1

17

Small-scale

0.747

High

403362

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

4

High-throughput

0.691

High

660327

SHO1
High osmolarity signaling protein SHO1

4

0

Small-scale

0.676

High

585859

CSK21
Casein kinase II subunit alpha

1

16

High-throughput

0.665

High

649562

KCC2
Calcium/calmodulin-dependent protein kinase II

1

5

High-throughput

0.647

High

660321

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

20

High-throughput

0.647

High

660333

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

17

High-throughput

0.647

High

660336

CLA4
Serine/threonine-protein kinase CLA4

1

17

Small-scale

0.647

High

660315

HOG1
Mitogen-activated protein kinase HOG1

1

16

High-throughput

0.621

High

660320

VPS21
Vacuolar protein sorting-associated protein 21

1

4

High-throughput

0.618

High

646302

RAD53
Serine/threonine-protein kinase RAD53

1

19

High-throughput

0.618

High

660342

SPH1
Protein SPH1

2

2

Small-scale

0.595

High

523109

HSP71
Heat shock protein SSA1

2

18

High-throughput

0.571

High

660328

DSE1
Protein DSE1

2

0

Small-scale

0.559

High

543872

SSB1
Ribosome-associated molecular chaperone SSB1

2

17

High-throughput

0.552

High

660329

SSB2
Ribosome-associated molecular chaperone SSB2

2

17

High-throughput

0.552

High

654757

URE2
Transcriptional regulator URE2

1

1

High-throughput

0.541

High

454404

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.536

High

660313

XPO1
Exportin-1

1

10

High-throughput

0.536

High

660324

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.536

High

660337

NST1
Stress response protein NST1

1

12

Small-scale

0.515

High

660339

EBS1
Nonsense-mediated mRNA decay factor EBS1

1

0

High-throughput

0.513

High

660344

PBP4
Protein PBP4

1

0

High-throughput

0.513

High

654699

SPA2
Protein SPA2

1

3

Small-scale

0.508

High

660330

BUD6
Bud site selection protein 6

1

1

Small-scale

0.508

High

660332

LSM1
LSM1-LSM7 complex subunit LSM1

1

1

High-throughput

0.508

High

660322

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

Small-scale

0.504

High

510216

HSP77
Import motor subunit, mitochondrial

1

20

Small-scale

0.501

High

518211

IF4A
ATP-dependent RNA helicase eIF4A

1

9

High-throughput

0.501

High

624453

RDS2
Regulator of drug sensitivity 2

1

1

High-throughput

0.501

High

660317

GLRX4
Monothiol glutaredoxin-4

1

3

High-throughput

0.501

High

660323

IFH1
Protein IFH1

1

6

High-throughput

0.489

High

660325

GDI1
Rab GDP-dissociation inhibitor

1

1

High-throughput

0.489

High

660314

MSB2
Signaling mucin MSB2

1

2

Small-scale

0.481

High

660326

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.480

High

660335

HGH1
Protein HGH1

1

0

High-throughput

0.480

High

481489

HSP73
Heat shock protein SSA3

1

18

Small-scale

0.479

High

660312

BEM1
Bud emergence protein 1

1

8

Small-scale

0.479

High

660319

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

1

High-throughput

0.470

High

660345

YD073
UPF0592 protein YDL073W

1

0

Small-scale

0.458

High

660346

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

381887

H4
Histone H4

1

4

Small-scale

0.457

High

660310

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.457

High

660347

YIG1
Protein YIG1

1

1

High-throughput

0.457

High

660338

UBC7
Ubiquitin-conjugating enzyme E2 7

1

9

High-throughput

0.457

High

525964

HSP72
Heat shock protein SSA2

1

18

High-throughput

0.445

High

660331

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.445

High

660341

FUS2
Nuclear fusion protein FUS2

1

0

Small-scale

0.438

High

660311

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

660334

MOG1
Nuclear import protein MOG1

1

2

High-throughput

0.437

High

619148

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.261

Low

613747

MDM10
Mitochondrial distribution and morphology protein 10

1

0

High-throughput

0.249

Low

660343

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

574850

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025