HitPredict

Interactor 1: H2AZ (P0C0S5)
Histone H2A.Z (H2A/z)
Gene: H2AZ1

Interactor 2: REQU (Q92785)
Zinc finger protein ubi-d4 (Apoptosis response zinc finger protein) (BRG1-associated factor 45D) (BAF45D) (D4, zinc and double PHD fingers family 2) (Protein requiem)
Gene: DPF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28242625, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 391
+	Hs
		555568 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		REQU_HUMAN (1-391): 1.89e-101: 307: 100.00
+	Hs
		594858 H2A1D_HUMAN (5-125): 7.06e-55: 169: 62.30		REQU_HUMAN (1-391): 1.89e-101: 307: 100.00
+	Hs
		1018640 H2A1H_HUMAN (5-125): 2.98e-55: 170: 61.48		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		470021 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		391675 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CHD3_HUMAN (43-382): 1.44e-49: 181: 13.23
+	Hs
		470113 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		KAT6A_HUMAN (76-387): 3.75e-43: 162: 26.48
+	Hs
		1059717 H2A2B_HUMAN (5-127): 9.2e-56: 171: 59.68		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		1059647 H2A2C_HUMAN (5-127): 3.47e-55: 170: 61.29		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		1059795 H2A1H_HUMAN (5-125): 2.98e-55: 170: 61.48		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		391704 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		470387 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		555466 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		CHD4_HUMAN (32-382): 5.17e-44: 165: 12.73
+	Hs
		470127 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		NSD1_HUMAN (101-375): 8.5e-35: 138: 17.97
+	Hs
		470105 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		PHF10_HUMAN (226-384): 1.03e-31: 127: 35.19
+	Hs
		391662 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		KMT2A_HUMAN (80-388): 8.66e-36: 141: 14.38
+	Hs
		470359 H2A1_HUMAN (5-125): 8.23e-55: 169: 61.48		KMT2A_HUMAN (80-388): 8.66e-36: 141: 14.38
+	Hs
		470198 H2AZ_HUMAN (1-128): 9.79e-62: 186: 100.00		BAZ2A_HUMAN (329-375): 3.73e-18: 88.7: 51.06
+	Hs
		152575 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		KMT2D_HUMAN (241-382): 8.36e-23: 102: 30.77
+	Hs
		555681 H2AX_HUMAN (5-124): 1.08e-54: 169: 61.98		BAZ2A_HUMAN (329-375): 3.73e-18: 88.7: 51.06
+	Hs
		391802 H2A1B_HUMAN (5-125): 9.18e-55: 169: 61.48		KMT2C_HUMAN (266-376): 2.95e-09: 61.3: 22.22