HitPredict

Interactor 1: A0AQH0 (A0AQH0)
Proteasome subunit beta
Gene: Prosbeta1

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 224 Dm			1 433
+	Hs
		700498 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Hs
		701105 PSB5_HUMAN (11-219): 9.7e-73: 223: 27.14		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Sc
		668378 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PRS7_YEAST (1-433): 5.55e-128: 379: 67.24
+	Sc
		750933 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PRS7_YEAST (1-433): 5.55e-128: 379: 67.24
+	Dm
		198056 Q8T8V8_DROME (1-199): 1.26e-81: 247: 28.00		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Sp
		206973 PSA5_SCHPO (4-215): 3.03e-74: 226: 18.39		PRS7_SCHPO (1-430): 4.39e-131: 386: 72.58
+	Sc
		721247 PSB5_YEAST (12-201): 4.67e-74: 227: 27.23		PRS7_YEAST (1-433): 5.55e-128: 379: 67.24
+	Dm
		47735 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Hs
		700508 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		700509 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Sc
		668404 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PRS8_YEAST (41-430): 1.24e-115: 346: 45.13
+	Dm
		47784 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		Q9V405_DROME (1-425): 2.69e-118: 352: 35.29
+	Hs
		700510 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS10_HUMAN (34-429): 9.58e-118: 350: 41.60
+	Dm
		47754 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Sc
		800857 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PRS8_YEAST (41-430): 1.24e-115: 346: 45.13
+	Hs
		700500 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84
+	Hs
		701129 PSB5_HUMAN (11-219): 9.7e-73: 223: 27.14		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Dm
		47825 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		Q9W414_DROME (33-429): 1.46e-116: 347: 42.75
+	Sc
		721271 PSB5_YEAST (12-201): 4.67e-74: 227: 27.23		PRS8_YEAST (41-430): 1.24e-115: 346: 45.13
+	Hs
		701110 PSB5_HUMAN (11-219): 9.7e-73: 223: 27.14		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84