HitPredict

Interactor 1: A0AQH0 (A0AQH0)
Proteasome subunit beta
Gene: Prosbeta1

Interactor 2: Q9W414 (Q9W414)
Regulatory particle triple-A ATPase 4 (EC 5.6.1.5)
Gene: Rpt4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 224 Dm			1 397
+	Hs
		700510 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS10_HUMAN (11-397): 4.75e-135: 393: 88.89
+	Hs
		700508 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS4_HUMAN (14-388): 2.39e-132: 388: 42.52
+	Dm
		47754 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		PRS4_DROME (13-388): 4.31e-132: 387: 42.41
+	Sc
		668402 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PRS10_YEAST (4-397): 2.55e-123: 365: 67.77
+	Dm
		198056 Q8T8V8_DROME (1-199): 1.26e-81: 247: 28.00		PRS8_DROME (1-395): 2.03e-121: 359: 44.94
+	Sc
		800854 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PRS10_YEAST (4-397): 2.55e-123: 365: 67.77
+	Dm
		47735 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		PRS8_DROME (1-395): 2.03e-121: 359: 44.94
+	Dm
		47784 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		Q9V405_DROME (3-391): 1.71e-121: 359: 40.62
+	Hs
		700500 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS6B_HUMAN (7-391): 1.79e-120: 357: 42.60
+	Sc
		721269 PSB5_YEAST (12-201): 4.67e-74: 227: 27.23		PRS10_YEAST (4-397): 2.55e-123: 365: 67.77
+	Hs
		700509 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS8_HUMAN (14-395): 2.09e-118: 351: 46.60
+	Sc
		668404 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PRS8_YEAST (15-395): 1.09e-114: 342: 45.14
+	Sc
		800857 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PRS8_YEAST (15-395): 1.09e-114: 342: 45.14
+	Sc
		668378 PSB2_YEAST (9-211): 1.44e-80: 243: 31.22		PRS7_YEAST (76-394): 3.04e-109: 330: 51.56
+	Sc
		750933 PSB1_YEAST (1-208): 3.46e-80: 240: 53.11		PRS7_YEAST (76-394): 3.04e-109: 330: 51.56
+	Sc
		721271 PSB5_YEAST (12-201): 4.67e-74: 227: 27.23		PRS8_YEAST (15-395): 1.09e-114: 342: 45.14
+	Hs
		700498 PSB9_HUMAN (7-213): 5.09e-79: 237: 50.73		PRS7_HUMAN (12-382): 2.4e-109: 329: 45.22
+	Dm
		47767 A0AQH0_DROME (1-224): 6e-78: 235: 100.00		Q7KMQ0_DROME (12-382): 2.28e-109: 329: 45.22
+	Sc
		721247 PSB5_YEAST (12-201): 4.67e-74: 227: 27.23		PRS7_YEAST (76-394): 3.04e-109: 330: 51.56
+	Sp
		206973 PSA5_SCHPO (4-215): 3.03e-74: 226: 18.39		PRS7_SCHPO (74-394): 1.81e-106: 322: 49.69