HitPredict

Interactor 1: S12A8 (A0AV02)
Solute carrier family 12 member 8 (Cation-chloride cotransporter 9)
Gene: SLC12A8

Interactor 2: GP182 (O15218)
G-protein coupled receptor 182
Gene: GPR182

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 714 Hs			1 404
+	Hs
		906981 S12A5_HUMAN (12-421): 5.43e-131: 417: 22.39		CCR4_HUMAN (22-371): 3.9e-71: 229: 22.88
+	Hs
		182697 YLAT2_HUMAN (7-477): 1.8e-101: 322: 15.35		GP182_HUMAN (1-404): 2.37e-84: 264: 100.00
+	Hs
		1101654 S12A9_HUMAN (38-420): 4.79e-108: 351: 27.21		GPR17_HUMAN (1-362): 3.32e-70: 227: 23.18
+	Hs
		957002 S12A9_HUMAN (38-420): 4.79e-108: 351: 27.21		CXCR4_HUMAN (22-352): 1.12e-70: 227: 21.86
+	Hs
		771107 S12A2_HUMAN (8-447): 3.63e-96: 324: 29.57		APJ_HUMAN (34-397): 1.62e-71: 231: 23.22
+	Hs
		669300 CTR1_HUMAN (8-409): 7.97e-85: 282: 13.70		ACKR3_HUMAN (20-368): 4.22e-88: 272: 29.53
+	Hs
		182474 CTR1_HUMAN (8-409): 7.97e-85: 282: 13.70		GP182_HUMAN (1-404): 2.37e-84: 264: 100.00
+	Hs
		182496 CTR2_HUMAN (2-451): 5.68e-84: 280: 13.76		GP182_HUMAN (1-404): 2.37e-84: 264: 100.00
+	Hs
		832381 S12A7_HUMAN (36-421): 4.62e-89: 303: 22.11		OPRD_HUMAN (9-376): 1.49e-72: 233: 21.43
+	Hs
		722406 CTR1_HUMAN (8-409): 7.97e-85: 282: 13.70		APJ_HUMAN (34-397): 1.62e-71: 231: 23.22
+	Hs
		722422 CTR1_HUMAN (8-409): 7.97e-85: 282: 13.70		CCR9_HUMAN (3-371): 3.09e-70: 227: 23.86
+	Hs
		722432 CTR1_HUMAN (8-409): 7.97e-85: 282: 13.70		CXCR4_HUMAN (22-352): 1.12e-70: 227: 21.86
+	Hs
		912652 CTR2_HUMAN (2-451): 5.68e-84: 280: 13.76		CXCR4_HUMAN (22-352): 1.12e-70: 227: 21.86
+	Hs
		912671 CTR2_HUMAN (2-451): 5.68e-84: 280: 13.76		GPR17_HUMAN (1-362): 3.32e-70: 227: 23.18
+	Hs
		141819 CTR1_HUMAN (8-409): 7.97e-85: 282: 13.70		ACKR2_HUMAN (43-331): 2.66e-32: 127: 33.33
+	Hs
		638400 CTR2_HUMAN (2-451): 5.68e-84: 280: 13.76		FPR1_HUMAN (54-357): 2.06e-24: 104: 26.28
+	Hs
		668976 CTR1_HUMAN (8-409): 7.97e-85: 282: 13.70		FPR2_HUMAN (53-346): 7.43e-23: 100: 26.33
+	Hs
		668981 CTR2_HUMAN (2-451): 5.68e-84: 280: 13.76		FPR2_HUMAN (53-346): 7.43e-23: 100: 26.33