HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: H2B1D (P58876)
Histone H2B type 1-D (H2B-clustered histone 5) (HIRA-interacting protein 2) (Histone H2B.1 B) (Histone H2B.b) (H2B/b)
Gene: H2BC5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35575683
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 685 Hs			1 126
+	Hs
		508099 UBC_HUMAN (1-685): 0: 857: 100.00		H2B2F_HUMAN (1-126): 3.92e-54: 167: 97.62
+	Hs
		508512 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1M_HUMAN (1-126): 4.47e-54: 167: 96.83
+	Hs
		449667 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1J_HUMAN (1-126): 1.25e-53: 166: 97.62
+	Hs
		507537 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1O_HUMAN (1-126): 5.45e-54: 166: 97.62
+	Hs
		508053 UBC_HUMAN (1-685): 0: 857: 100.00		H2B2E_HUMAN (1-126): 9.95e-54: 166: 98.41
+	Hs
		508382 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1H_HUMAN (1-126): 8.92e-54: 166: 98.41
+	Hs
		256748 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1K_HUMAN (1-126): 2.12e-53: 165: 98.41
+	Hs
		507591 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1B_HUMAN (1-126): 1.78e-53: 165: 97.62
+	Hs
		507741 UBC_HUMAN (1-685): 0: 857: 100.00		H2BFS_HUMAN (1-126): 1.65e-53: 165: 96.83
+	Hs
		507791 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1C_HUMAN (1-126): 1.72e-53: 165: 99.21
+	Hs
		508510 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1N_HUMAN (1-126): 3.51e-53: 164: 99.21
+	Hs
		508513 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1L_HUMAN (1-126): 3.74e-52: 162: 97.62
+	Hs
		508268 UBC_HUMAN (1-685): 0: 857: 100.00		H2B3B_HUMAN (1-126): 2.69e-51: 160: 95.24
+	Hs
		508392 UBC_HUMAN (1-685): 0: 857: 100.00		H2B1A_HUMAN (1-126): 5.56e-46: 146: 85.04
+	Sc
		381366 UBI4P_YEAST (381-685): 4.09e-126: 380: 95.74		H2B2_YEAST (3-125): 6.01e-40: 131: 70.73
+	Dm
		380896 R9PY16_DROME (457-685): 1.03e-83: 268: 90.39		H2B_DROME (36-126): 8.31e-46: 146: 94.51
+	Hs
		449700 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1J_HUMAN (1-126): 1.25e-53: 166: 97.62
+	Hs
		659885 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1O_HUMAN (1-126): 5.45e-54: 166: 97.62
+	Hs
		256822 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1K_HUMAN (1-126): 2.12e-53: 165: 98.41
+	Hs
		754785 RS27A_HUMAN (609-684): 7.26e-41: 148: 100.00		H2B1B_HUMAN (1-126): 1.78e-53: 165: 97.62