Interactor 1: BMP2 (P12643)
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
Gene: BMP2

Interactor 2: BMP2 (P12643)
Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
Gene: BMP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 16672363, 23122408
Identification Methods x-ray crystallography, cross-linking study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide, TGFb_propeptide~TGFb_propeptide
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001501 - skeletal system development
GO:0001649 - osteoblast differentiation
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0001666 - response to hypoxia
and 105 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 396
Hs

1 396
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024