HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: TENS4 (Q8IZW8)
Tensin-4 (C-terminal tensin-like protein)
Gene: TNS4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	24728074
Identification Methods	pull down, fluorescence polarization spectroscopy
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 715
+	Hs
		520383 ANDR_HUMAN (1-920): 0: 966: 100.00		TENS1_HUMAN (9-712): 6.13e-69: 248: 30.27
+	Hs
		519699 ANDR_HUMAN (1-920): 0: 966: 100.00		SRC_HUMAN (287-582): 1.34e-21: 101: 14.56
+	Hs
		520149 ANDR_HUMAN (1-920): 0: 966: 100.00		SRCAP_HUMAN (43-618): 3.86e-09: 62.5: 10.07
+	Hs
		520414 ANDR_HUMAN (1-920): 0: 966: 100.00		CHD7_HUMAN (25-415): 3.52e-09: 62.5: 9.16
+	Hs
		520207 ANDR_HUMAN (1-920): 0: 966: 100.00		KMT2C_HUMAN (2-469): 9.27e-09: 61.3: 7.64
+	Hs
		404215 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		TENS4_HUMAN (1-715): 7.69e-95: 311: 100.00
+	Hs
		1228513 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		TENS3_HUMAN (1-714): 2.22e-77: 273: 26.68
+	Hs
		395433 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		MUC1_HUMAN (70-615): 3.41e-23: 107: 9.91
+	Hs
		395400 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		SRC_HUMAN (287-582): 1.34e-21: 101: 14.56
+	Rn
		439610 ESR1_RAT (378-904): 2.2e-130: 406: 20.94		SRC_RAT (287-582): 3.09e-22: 103: 14.56
+	Mm
		431322 ESR1_MOUSE (378-904): 2.51e-129: 403: 21.30		SRC_MOUSE (287-582): 2.52e-22: 103: 14.89
+	Hs
		397115 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		CHD7_HUMAN (25-415): 3.52e-09: 62.5: 9.16
+	Hs
		396547 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		KMT2C_HUMAN (2-469): 9.27e-09: 61.3: 7.64
+	Hs
		403785 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		SRC_HUMAN (287-582): 1.34e-21: 101: 14.56
+	Hs
		557079 RXRA_HUMAN (392-902): 7.08e-120: 374: 19.84		SRC_HUMAN (287-582): 1.34e-21: 101: 14.56
+	Hs
		590324 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		MUC1_HUMAN (70-615): 3.41e-23: 107: 9.91
+	Hs
		557411 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		SRC_HUMAN (287-582): 1.34e-21: 101: 14.56
+	Hs
		404499 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		CHD7_HUMAN (25-415): 3.52e-09: 62.5: 9.16
+	Hs
		925735 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		SC24C_HUMAN (202-494): 4.55e-10: 65.1: 12.09
+	Hs
		1338263 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		KMT2C_HUMAN (2-469): 9.27e-09: 61.3: 7.64