Interactor 1: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2
Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.946 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 12137781, 33961781, 18835031, 14980220 |
| Identification Methods | affinity chromatography technology, unspecified method, pull down, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~Bcl-2, BH4~Bcl-2, BH4~BH4 |
| Common GO terms | GO:0001541 - ovarian follicle development GO:0001836 - release of cytochrome c from mitochondria GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane and 22 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025