HitPredict

Interactor 1: TYW1 (Q9NV66)
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein)
Gene: TYW1

Interactor 2: PCDGL (Q9Y5F7)
Protocadherin gamma-C4 (PCDH-gamma-C4)
Gene: PCDHGC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 938
+	Hs
		1346338 TYW1_HUMAN (1-732): 0: 1128: 100.00		PCDG5_HUMAN (1-923): 0: 1017: 47.08
+	Hs
		1346339 TYW1_HUMAN (1-732): 0: 1128: 100.00		PCDA3_HUMAN (28-920): 0: 937: 36.67
+	Hs
		1328454 TYW1_HUMAN (1-732): 0: 1128: 100.00		PCDC1_HUMAN (17-700): 1e-175: 537: 45.06
+	Hs
		1346335 TYW1_HUMAN (1-732): 0: 1128: 100.00		PCDB3_HUMAN (13-729): 7.01e-177: 534: 42.62
+	Hs
		1346337 TYW1_HUMAN (1-732): 0: 1128: 100.00		PCDGH_HUMAN (4-447): 1.4e-104: 348: 28.41
+	Hs
		1346331 TYW1_HUMAN (1-732): 0: 1128: 100.00		PCDGG_HUMAN (2-447): 1.14e-100: 337: 28.51