HitPredict

Interactor 1: IF4A2 (P10630)
Eukaryotic initiation factor 4A-II (eIF-4A-II) (eIF4A-II) (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: Eif4a2

Interactor 2: IF4H (Q9WUK2)
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein homolog)
Gene: Eif4h

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 407 Mm			1 248
+	Hs
		953894 IF4A1_HUMAN (3-407): 1.31e-159: 457: 89.88		IF4H_HUMAN (1-248): 4.78e-54: 176: 98.79
+	Mm
		954061 IF4A1_MOUSE (3-407): 1.31e-159: 457: 89.88		IF4H_MOUSE (1-248): 1.03e-53: 175: 100.00
+	At
		102087 F4JEL4_ARATH (16-385): 6.15e-175: 496: 71.62		RBG7_ARATH (41-117): 1.05e-28: 108: 25.32
+	Hs
		660569 IF4A1_HUMAN (3-407): 1.31e-159: 457: 89.88		IF4B_HUMAN (33-208): 4.6e-32: 125: 32.22
+	Hs
		550200 IF4A1_HUMAN (3-407): 1.31e-159: 457: 89.88		PABP1_HUMAN (33-206): 1.03e-19: 89.8: 16.20
+	Hs
		953872 IF4A1_HUMAN (3-407): 1.31e-159: 457: 89.88		PABP4_HUMAN (33-126): 1.26e-19: 89.4: 18.75
+	Hs
		953884 IF4A1_HUMAN (3-407): 1.31e-159: 457: 89.88		RBM39_HUMAN (36-210): 8.37e-18: 84: 18.18
+	Mm
		915269 IF4A1_MOUSE (3-407): 1.31e-159: 457: 89.88		TIA1_MOUSE (10-224): 4.6e-17: 81.3: 13.36
+	Hs
		141326 DDX3X_HUMAN (2-406): 1.08e-126: 382: 29.51		IF4B_HUMAN (33-208): 4.6e-32: 125: 32.22
+	Hs
		193085 DDX3Y_HUMAN (2-406): 1.05e-126: 382: 29.98		IF4B_HUMAN (33-208): 4.6e-32: 125: 32.22
+	Hs
		1120263 DDX17_HUMAN (25-407): 7.84e-131: 394: 31.20		HNRPD_HUMAN (2-213): 3.22e-23: 98.2: 15.49
+	Hs
		608597 DDX5_HUMAN (10-407): 2.11e-132: 395: 30.30		RBM39_HUMAN (36-210): 8.37e-18: 84: 18.18
+	Hs
		1127053 DDX17_HUMAN (25-407): 7.84e-131: 394: 31.20		RBM39_HUMAN (36-210): 8.37e-18: 84: 18.18
+	Mm
		915297 DDX17_MOUSE (25-407): 8.62e-132: 394: 31.20		TIA1_MOUSE (10-224): 4.6e-17: 81.3: 13.36
+	Mm
		915325 Q8BTS0_MOUSE (22-407): 3.43e-132: 394: 30.96		TIA1_MOUSE (10-224): 4.6e-17: 81.3: 13.36
+	Hs
		141299 DDX3X_HUMAN (2-406): 1.08e-126: 382: 29.51		PABP1_HUMAN (33-206): 1.03e-19: 89.8: 16.20
+	Hs
		141463 DDX3X_HUMAN (2-406): 1.08e-126: 382: 29.51		PABP4_HUMAN (33-126): 1.26e-19: 89.4: 18.75
+	Hs
		550156 IF4A3_HUMAN (3-407): 4.46e-129: 379: 67.65		PABP1_HUMAN (33-206): 1.03e-19: 89.8: 16.20
+	Mm
		1000097 DDX5_MOUSE (22-407): 2.57e-132: 394: 30.96		TIAR_MOUSE (10-224): 2.44e-14: 73.6: 10.14
+	Sc
		666407 DBP2_YEAST (22-405): 1.02e-131: 390: 32.65		NSR1_YEAST (30-150): 1.55e-09: 59.4: 21.26