Protein: IF4H
Eukaryotic translation initiation factor 4H (eIF-4H) (Williams-Beuren syndrome chromosomal region 1 protein)

Gene: IF4H, EIF4H
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q15056

Gene Ontology (top 5):
GO:0001731 - formation of translation preinitiation complex
GO:0003723 - RNA binding
GO:0003743 - translation initiation factor activity
GO:0005829 - cytosol
GO:0006446 - regulation of translational initiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

783582

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

12

High-throughput

0.691

High

1140265

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

1

15

High-throughput

0.691

High

1140268

CK068
UPF0696 protein C11orf68

5

0

High-throughput

0.691

High

953894

IF4A1
Eukaryotic initiation factor 4A-I

2

20

Small-scale

0.624

High

170148

AURKA
Aurora kinase A

1

12

High-throughput

0.618

High

685574

U2AF2
Splicing factor U2AF 65 kDa subunit

1

20

High-throughput

0.618

High

891167

GSK3A
Glycogen synthase kinase-3 alpha

1

8

High-throughput

0.618

High

891561

GSK3B
Glycogen synthase kinase-3 beta

1

11

High-throughput

0.618

High

1032976

EWS
RNA-binding protein EWS

1

14

High-throughput

0.618

High

1100788

G3BP1
Ras GTPase-activating protein-binding protein 1

1

20

High-throughput

0.618

High

1122487

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

7

High-throughput

0.618

High

1140276

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.618

High

629877

BTF3
Transcription factor BTF3

2

2

High-throughput

0.611

High

1140262

FBX17
F-box only protein 17

2

2

High-throughput

0.606

High

286206

CSDE1
Cold shock domain-containing protein E1

1

0

High-throughput

0.586

High

1140260

DLG3
Disks large homolog 3

2

0

High-throughput

0.580

High

1140269

PICK1
PRKCA-binding protein

2

0

High-throughput

0.580

High

1140273

SPG21
Maspardin

2

0

High-throughput

0.580

High

1140257

LNX1
E3 ubiquitin-protein ligase LNX

2

1

High-throughput

0.573

High

529822

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.536

High

765535

BMI1
Polycomb complex protein BMI-1

1

17

High-throughput

0.536

High

894550

GDIB
Rab GDP dissociation inhibitor beta

1

3

High-throughput

0.536

High

1140256

RIN3
Ras and Rab interactor 3

1

4

High-throughput

0.536

High

1140278

SAR1B
Small COPII coat GTPase SAR1B

1

4

High-throughput

0.536

High

1140272

TLR7
Toll-like receptor 7

2

2

High-throughput

0.533

High

1140251

NEK10
Serine/threonine-protein kinase Nek10

1

7

High-throughput

0.514

High

389372

FINC
Fibronectin

1

7

High-throughput

0.489

High

345845

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

17

High-throughput

0.479

High

372074

MYC
Myc proto-oncogene protein

1

15

High-throughput

0.479

High

375533

RASK
GTPase KRas

1

9

High-throughput

0.479

High

474691

VIME
Vimentin

1

6

High-throughput

0.479

High

556089

CADH1
Cadherin-1

1

2

High-throughput

0.479

High

659482

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.479

High

791396

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

807429

IF4A3
Eukaryotic initiation factor 4A-III

1

20

High-throughput

0.479

High

833271

PERI
Peripherin

1

6

High-throughput

0.479

High

954137

RS20
Small ribosomal subunit protein uS10

1

8

High-throughput

0.479

High

980782

H2B1C
Histone H2B type 1-C/E/F/G/I

1

15

High-throughput

0.479

High

1085556

FOXO1
Forkhead box protein O1

1

2

High-throughput

0.479

High

1089204

TRI26
Tripartite motif-containing protein 26

1

10

Small-scale

0.479

High

1094546

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.479

High

1134889

CUL7
Cullin-7

1

9

High-throughput

0.479

High

1140246

MARE1
Microtubule-associated protein RP/EB family member 1

1

3

High-throughput

0.479

High

1140253

NAA40
N-alpha-acetyltransferase 40

1

3

High-throughput

0.479

High

1140255

TNIP2
TNFAIP3-interacting protein 2

1

4

High-throughput

0.479

High

1140258

BICD2
Protein bicaudal D homolog 2

1

9

High-throughput

0.479

High

1140259

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

1140263

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.479

High

1140266

BAG1
BAG family molecular chaperone regulator 1

1

2

High-throughput

0.479

High

1140267

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.479

High

1140274

DJB11
DnaJ homolog subfamily B member 11

1

4

High-throughput

0.479

High

1140275

DNJB4
DnaJ homolog subfamily B member 4

1

6

High-throughput

0.479

High

1140277

SEC63
Translocation protein SEC63 homolog

1

4

High-throughput

0.479

High

254610

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.458

High

404793

PRIO
Major prion protein

1

2

High-throughput

0.445

High

934634

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.445

High

1140248

NCLX
Mitochondrial sodium/calcium exchanger protein

1

1

High-throughput

0.445

High

1140254

S2611
Sodium-independent sulfate anion transporter

1

1

High-throughput

0.445

High

1140264

OTUB1
Ubiquitin thioesterase OTUB1

1

2

High-throughput

0.445

High

105963

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

259975

BRD4
Bromodomain-containing protein 4

1

7

High-throughput

0.437

High

318779

RHBT1
Rho-related BTB domain-containing protein 1

1

10

High-throughput

0.437

High

376834

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

2

High-throughput

0.437

High

411961

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.437

High

551057

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.437

High

588741

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.437

High

606789

CEBPB
CCAAT/enhancer-binding protein beta

1

12

High-throughput

0.437

High

695506

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

768239

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

1140247

BRD10
Uncharacterized bromodomain-containing protein 10

1

3

High-throughput

0.437

High

1140250

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1140252

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.437

High

133510

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.426

High

1140270

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.426

High

619802

VCAM1
Vascular cell adhesion protein 1

1

7

High-throughput

0.407

High

886874

CEBPA
CCAAT/enhancer-binding protein alpha

1

12

High-throughput

0.373

High

1140261

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

1140271

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.249

Low

1140249

LIN54
Protein lin-54 homolog

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025