HitPredict

Interactor 1: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Interactor 2: PRDX1 (Q06830)
Peroxiredoxin-1 (EC 1.11.1.24) (Natural killer cell-enhancing factor A) (NKEF-A) (Proliferation-associated gene protein) (PAG) (Thioredoxin peroxidase 2) (Thioredoxin-dependent peroxide reductase 2) (Thioredoxin-dependent peroxiredoxin 1)
Gene: PRDX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	26618866, 31324722, 29924966
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1480 Hs			1 199
+	Hs
		528644 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX2_HUMAN (1-198): 2.38e-103: 297: 77.78
+	Hs
		528616 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX3_HUMAN (2-197): 1.85e-98: 287: 62.76
+	Hs
		529062 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX4_HUMAN (4-197): 4.03e-95: 279: 69.59
+	Hs
		528615 CFTR_HUMAN (1-1480): 0: 1031: 100.00		PRDX6_HUMAN (4-197): 5.84e-67: 206: 28.50