HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: GNAZ (P19086)
Guanine nucleotide-binding protein G(z) subunit alpha (G(x) alpha chain) (Gz-alpha)
Gene: GNAZ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030425 - dendrite GO:0044297 - cell body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 355
+	Hs
		418576 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNAI2_HUMAN (1-354): 5.01e-177: 496: 66.38
+	Hs
		529571 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNAI1_HUMAN (1-354): 1.84e-176: 495: 67.23
+	Hs
		482573 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNAO_HUMAN (1-354): 5.83e-175: 491: 60.45
+	Hs
		475879 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNAI3_HUMAN (1-354): 1.25e-173: 488: 67.23
+	Hs
		529570 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNAS2_HUMAN (1-354): 2.37e-167: 473: 37.22
+	Hs
		529353 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNAQ_HUMAN (1-354): 3.48e-167: 472: 47.89
+	Hs
		529158 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNA11_HUMAN (1-354): 9.9e-164: 463: 46.76
+	Hs
		349311 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNA14_HUMAN (3-354): 1.03e-161: 458: 48.16
+	Rn
		620025 TAU_RAT (1-758): 3.21e-76: 263: 72.11		GNAO_RAT (1-354): 4.03e-173: 487: 59.89
+	Rn
		98716 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		GNAO_RAT (1-354): 4.03e-173: 487: 59.89
+	Hs
		529796 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		GNA13_HUMAN (2-354): 2.73e-156: 445: 39.17
+	Mm
		73958 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		GNAI1_MOUSE (1-354): 1.84e-176: 495: 67.23
+	Mm
		475857 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		GNAI2_MOUSE (1-354): 5.1e-176: 494: 66.10
+	Mm
		267010 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		GNAZ_MOUSE (1-355): 1.92e-168: 475: 98.31
+	Mm
		530706 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		GNAQ_MOUSE (1-354): 2.02e-167: 472: 47.89
+	Mm
		530705 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		GNA11_MOUSE (1-354): 6.36e-165: 466: 46.20