HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: WASF1 (Q92558)
Actin-binding protein WASF1 (Protein WAVE-1) (Verprolin homology domain-containing protein 1) (Wiskott-Aldrich syndrome protein family member 1) (WASP family protein member 1)
Gene: WASF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:1990416 - cellular response to brain-derived neurotrophic factor stimulus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 559
+	Hs
		530592 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		WASF3_HUMAN (1-557): 6.8e-44: 164: 45.99
+	Hs
		529703 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		EP300_HUMAN (77-554): 7.94e-29: 124: 14.91
+	Hs
		323826 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SC31A_HUMAN (184-539): 2.99e-28: 122: 12.57
+	Rn
		620073 TAU_RAT (1-758): 3.21e-76: 263: 72.11		SYNJ1_RAT (123-553): 2.32e-35: 144: 12.53
+	Rn
		98765 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		SYNJ1_RAT (123-553): 2.32e-35: 144: 12.53
+	Mm
		92766 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		D3Z656_MOUSE (123-535): 4.09e-36: 146: 13.52
+	Hs
		215898 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SYNJ1_HUMAN (284-555): 3.16e-12: 71.7: 13.43
+	Hs
		529408 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SC24C_HUMAN (164-476): 3.88e-10: 65.1: 12.65
+	Hs
		590279 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		EP300_HUMAN (77-554): 7.94e-29: 124: 14.91
+	Mm
		236881 MAP4_MOUSE (11-720): 3.02e-34: 143: 17.29		ACK1_MOUSE (162-530): 9.43e-22: 102: 18.09
+	Hs
		590235 MUC1_HUMAN (39-730): 2.41e-41: 165: 11.50		MUC1_HUMAN (83-405): 6.5e-10: 64.4: 11.39
+	Hs
		1067330 MDC1_HUMAN (31-732): 1.31e-18: 93.5: 10.48		EP300_HUMAN (77-554): 7.94e-29: 124: 14.91
+	Hs
		1067448 SRCAP_HUMAN (168-756): 9.46e-12: 71.2: 11.72		EP300_HUMAN (77-554): 7.94e-29: 124: 14.91
+	Hs
		698270 MAP4_HUMAN (22-721): 3.01e-10: 66.2: 9.24		EP300_HUMAN (77-554): 7.94e-29: 124: 14.91
+	Hs
		161457 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		EP300_HUMAN (77-554): 7.94e-29: 124: 14.91
+	Dm
		119660 M9PB30_DROME (3-585): 4.93e-18: 91.6: 9.03		M9PB30_DROME (82-553): 3.63e-09: 62: 13.13
+	Hs
		130585 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		SPT5H_HUMAN (136-461): 6.21e-14: 77.1: 12.99
+	Hs
		130304 KMT2D_HUMAN (3-747): 3.75e-09: 62.7: 10.76		SPT5H_HUMAN (136-461): 6.21e-14: 77.1: 12.99
+	Hs
		1401422 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		CHD7_HUMAN (42-546): 6.47e-12: 70.9: 10.42
+	Hs
		925743 CIC_HUMAN (10-717): 9.83e-10: 64.7: 8.46		SC24C_HUMAN (164-476): 3.88e-10: 65.1: 12.65