HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: DBNL (Q9UJU6)
Drebrin-like protein (Cervical SH3P7) (Cervical mucin-associated protein) (Drebrin-F) (HPK1-interacting protein of 55 kDa) (HIP-55) (SH3 domain-containing protein 7)
Gene: DBNL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 2 others more... GO:0007416 - synapse assembly GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 430
+	Hs
		529885 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		DREB_HUMAN (3-379): 4.31e-60: 208: 29.19
+	Mm
		530933 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		DREB_MOUSE (3-378): 3.93e-57: 201: 27.70
+	Hs
		530330 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PACN1_HUMAN (95-429): 5.72e-37: 142: 16.39
+	Hs
		530580 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		PACN2_HUMAN (87-430): 6.8e-37: 142: 15.24
+	Hs
		529791 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SRC8_HUMAN (120-430): 1.99e-34: 136: 25.71
+	Hs
		530633 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SHLB1_HUMAN (90-429): 2.54e-34: 133: 15.27
+	Hs
		530287 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		SH3G2_HUMAN (167-429): 6.23e-34: 131: 17.87
+	Hs
		529773 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		COTL1_HUMAN (3-145): 1.36e-33: 124: 22.76
+	Rn
		620079 TAU_RAT (1-758): 3.21e-76: 263: 72.11		SRC8_RAT (119-430): 5.08e-35: 137: 26.58
+	Rn
		98772 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		SRC8_RAT (119-430): 5.08e-35: 137: 26.58
+	Rn
		620084 TAU_RAT (1-758): 3.21e-76: 263: 72.11		BAIP2_RAT (102-430): 3.6e-32: 130: 13.92
+	Rn
		98778 F1LST4_RAT (1-757): 7.75e-76: 262: 72.21		BAIP2_RAT (102-430): 3.6e-32: 130: 13.92
+	Mm
		530827 TAU_MOUSE (1-758): 8.57e-72: 250: 70.17		PACN1_MOUSE (95-429): 8.17e-33: 130: 14.88
+	Hs
		529809 TAU_HUMAN (1-758): 6.41e-90: 300: 100.00		LASP1_HUMAN (246-429): 2.87e-15: 77.3: 24.24
+	Hs
		571698 PCLO_HUMAN (21-757): 4.9e-30: 130: 10.00		HCLS1_HUMAN (122-430): 5.8e-36: 140: 23.99
+	Hs
		215945 SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41		SH3G1_HUMAN (166-429): 3.71e-35: 135: 17.74
+	Hs
		215920 SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41		MYO1E_HUMAN (147-429): 4.39e-33: 134: 14.84
+	Hs
		215946 SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41		SH3G2_HUMAN (167-429): 6.23e-34: 131: 17.87
+	Hs
		215885 SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41		VINEX_HUMAN (286-429): 9.11e-14: 75.4: 17.69
+	Hs
		215925 SYNJ1_HUMAN (173-636): 8.49e-14: 77.6: 14.41		ITSN1_HUMAN (277-429): 1.05e-09: 62.7: 17.83