HitPredict

Interactor 1: CO6 (P13671)
Complement component C6
Gene: C6

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 934 Hs			1 217
+	Hs
		532040 CO6_HUMAN (1-934): 0: 691: 100.00		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		337331 CO6_HUMAN (1-934): 0: 691: 100.00		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46
+	Hs
		411974 CO6_HUMAN (1-934): 0: 691: 100.00		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		441718 CFAH_HUMAN (547-932): 6.73e-19: 94.7: 15.97		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		557726 CSMD2_HUMAN (473-933): 2.3e-43: 174: 13.20		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		337494 CSMD2_HUMAN (473-933): 2.3e-43: 174: 13.20		ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46
+	Hs
		412241 CSMD2_HUMAN (473-933): 2.3e-43: 174: 13.20		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		433241 MCP_HUMAN (603-813): 4.39e-25: 110: 14.58		YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91
+	Hs
		522746 MCP_HUMAN (603-813): 4.39e-25: 110: 14.58		SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58
+	Hs
		433884 UNC5B_HUMAN (80-190): 1.83e-16: 86.4: 17.07		LYN_HUMAN (129-215): 1.44e-11: 65: 22.47