Interactor 1: EI2BA (P14741)
Translation initiation factor eIF2B subunit alpha (GCD complex subunit GCN3) (Guanine nucleotide exchange factor subunit GCN3) (Translational activator GCN3) (eIF2B GDP-GTP exchange factor subunit alpha)
Gene: GCN3

Interactor 2: EI2BE (P32501)
Translation initiation factor eIF2B subunit epsilon (GCD complex subunit GCD6) (Guanine nucleotide exchange factor subunit GCD6) (eIF2B GDP-GTP exchange factor subunit epsilon)
Gene: GCD6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 8336705, 11805826, 11805837, 10805739, 7565788, 10852917, 16554755, 16429126, 37968396, 20805354
Identification Methods coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, biochemical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~NTP_transferase
Common GO terms GO:0002183 - cytoplasmic translational initiation
GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 305
Sc

1 712
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Sp
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024