HitPredict

Interactor 1: SPTN1 (P16086)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain)
Gene: Sptan1

Interactor 2: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2472 Rn			1 752
+	Hs
		496988 SPTN1_HUMAN (3-2098): 6.08e-80: 297: 22.88		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Rn
		94140 SPTN1_RAT (3-1701): 3.36e-48: 193: 21.65		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		582039 SPTN2_RAT (1652-2340): 1.3e-22: 108: 19.24		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94264 SPTN2_RAT (1652-2340): 1.3e-22: 108: 19.24		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		497051 PLEC_HUMAN (1-1272): 1.62e-38: 161: 9.94		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		965102 SPTN1_HUMAN (3-2098): 6.08e-80: 297: 22.88		ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43
+	Hs
		497586 SPTN4_HUMAN (961-2380): 1.24e-29: 132: 14.51		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		164558 SPTN2_HUMAN (1652-2318): 6.59e-23: 110: 19.85		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496865 SPTB2_HUMAN (1-521): 1.54e-19: 99: 31.55		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496188 ACTN1_HUMAN (1862-2210): 4.47e-11: 70.9: 22.25		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		211474 ACTN4_HUMAN (1827-2219): 8.31e-10: 66.6: 20.86		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496176 DMD_HUMAN (1-707): 2.06e-09: 65.5: 13.61		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Mm
		561172 SPTN1_MOUSE (3-1701): 3.36e-48: 193: 21.71		ANK2_MOUSE (184-606): 1.18e-23: 109: 16.21
+	Hs
		503287 PLEC_HUMAN (1-1272): 1.62e-38: 161: 9.94		MTAP2_HUMAN (42-752): 4.53e-33: 139: 24.66
+	Hs
		965174 MACF1_HUMAN (803-2418): 2.95e-27: 124: 10.15		ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43
+	Hs
		164604 SPTN2_HUMAN (1652-2318): 6.59e-23: 110: 19.85		ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43
+	Hs
		963292 SPTB2_HUMAN (1-521): 1.54e-19: 99: 31.55		ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43
+	Hs
		503257 ACTN1_HUMAN (1862-2210): 4.47e-11: 70.9: 22.25		MTAP2_HUMAN (42-752): 4.53e-33: 139: 24.66
+	Dm
		54271 A1Z9I8_DROME (1-737): 1.23e-26: 122: 17.36		Q9VLS7_DROME (3-541): 3.66e-12: 72.4: 11.77
+	Hs
		513849 DMD_HUMAN (1-707): 2.06e-09: 65.5: 13.61		ANK2_HUMAN (184-667): 3.72e-25: 114: 15.43