HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 1102
+	Hs
		391829 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1087074 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		555529 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		UBP48_HUMAN (206-572): 1.45e-102: 349: 26.90
+	Hs
		555508 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		U17L2_HUMAN (158-684): 1.09e-103: 338: 19.05
+	Mm
		1113505 H2A1H_MOUSE (1-128): 2.85e-66: 198: 91.41		UBP48_MOUSE (206-572): 1.33e-102: 349: 27.45
+	Hs
		391769 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP48_HUMAN (206-572): 1.45e-102: 349: 26.90
+	Hs
		1087036 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP48_HUMAN (206-572): 1.45e-102: 349: 26.90
+	Hs
		391971 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		260922 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		UBP48_HUMAN (206-572): 1.45e-102: 349: 26.90
+	Hs
		1087135 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		391943 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13
+	Hs
		1312240 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13
+	Hs
		261028 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13
+	Hs
		391756 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBP51_HUMAN (61-525): 3.06e-95: 321: 16.58
+	Hs
		1087027 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP51_HUMAN (61-525): 3.06e-95: 321: 16.58
+	Hs
		905382 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP46_HUMAN (204-522): 1.27e-91: 299: 25.50
+	Hs
		259285 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		UBP12_HUMAN (189-522): 1.4e-89: 294: 25.55
+	Sc
		392501 H2A2_YEAST (16-124): 4.61e-53: 165: 82.57		UBP8_YEAST (131-519): 2.12e-90: 300: 21.98