HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: LIN41 (Q2Q1W2)
E3 ubiquitin-protein ligase TRIM71 (EC 2.3.2.27) (Protein lin-41 homolog) (RING-type E3 ubiquitin transferase TRIM71) (Tripartite motif-containing protein 71)
Gene: TRIM71

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 868
+	Hs
		489071 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		LIN41_HUMAN (1-868): 0: 707: 100.00
+	Hs
		971195 H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07		LIN41_HUMAN (1-868): 0: 707: 100.00
+	Ce
		136810 UNC89_CAEEL (3-191): 1.3e-15: 77.2: 22.80		LIN41_CAEEL (112-868): 7.35e-135: 432: 31.82
+	Hs
		489240 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		TRI56_HUMAN (111-868): 2.45e-106: 347: 16.86
+	Hs
		559322 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		RO52_HUMAN (185-608): 5.17e-97: 313: 14.45
+	Hs
		559395 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		TIF1B_HUMAN (195-490): 1.02e-84: 290: 25.25
+	Hs
		183320 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		MEFV_HUMAN (21-610): 5.96e-74: 259: 15.52
+	Hs
		559783 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		559925 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		TRIM7_HUMAN (174-608): 4.58e-74: 253: 14.61
+	Hs
		489116 H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		559145 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		TRI67_HUMAN (50-571): 1.02e-71: 253: 16.47
+	Hs
		559241 H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25		TRIM7_HUMAN (174-608): 4.58e-74: 253: 14.61