HitPredict

Interactor 1: K2C5 (P13647)
Keratin, type II cytoskeletal 5 (58 kDa cytokeratin) (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (Type-II keratin Kb5)
Gene: KRT5

Interactor 2: EFNA1 (P20827)
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]
Gene: EFNA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23686814
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 590 Hs			1 205
+	Hs
		635242 K22E_HUMAN (140-484): 3.02e-174: 509: 71.88		EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00
+	Hs
		777429 K22E_HUMAN (140-484): 3.02e-174: 509: 71.88		EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00
+	Hs
		777430 K22E_HUMAN (140-484): 3.02e-174: 509: 71.88		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		407252 K2C6B_HUMAN (2-505): 1.51e-89: 289: 79.56		EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00
+	Hs
		635245 K2C6C_HUMAN (2-505): 3.09e-89: 288: 79.17		EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00
+	Hs
		385238 K2C6A_HUMAN (2-505): 1.61e-85: 278: 79.17		EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00
+	Hs
		566347 K2C5_HUMAN (1-590): 1.3e-98: 313: 100.00		EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00
+	Hs
		914291 K2C73_HUMAN (1-589): 1.61e-101: 319: 51.27		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		566348 K2C5_HUMAN (1-590): 1.3e-98: 313: 100.00		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		407264 K2C6B_HUMAN (2-505): 1.51e-89: 289: 79.56		EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00
+	Hs
		876454 K2C6C_HUMAN (2-505): 3.09e-89: 288: 79.17		EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00
+	Hs
		914199 K2C71_HUMAN (1-558): 3.89e-87: 281: 51.79		EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00
+	Hs
		385251 K2C6A_HUMAN (2-505): 1.61e-85: 278: 79.17		EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00
+	Hs
		914240 KRT83_HUMAN (70-550): 1.82e-92: 294: 47.10		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		407265 K2C6B_HUMAN (2-505): 1.51e-89: 289: 79.56		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		914241 KRT85_HUMAN (1-483): 3.06e-90: 289: 50.31		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		876455 K2C6C_HUMAN (2-505): 3.09e-89: 288: 79.17		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		385252 K2C6A_HUMAN (2-505): 1.61e-85: 278: 79.17		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		914352 KRT82_HUMAN (1-561): 1.72e-84: 274: 45.81		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88
+	Hs
		914315 KRT35_HUMAN (52-526): 1.88e-70: 235: 23.37		EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88