HitPredict

Interactor 1: K2C6C (P48668)
Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK-6C) (Cytokeratin-6E) (CK-6E) (Keratin K6h) (Keratin-6C) (K6C) (Type-II keratin Kb12)
Gene: KRT6C

Interactor 2: EFNA4 (P52798)
Ephrin-A4 (EPH-related receptor tyrosine kinase ligand 4) (LERK-4)
Gene: EFNA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23686814
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 564 Hs			1 201
+	Hs
		407417 K2C1_HUMAN (128-494): 2.59e-165: 486: 73.57		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		407390 K2C1_HUMAN (128-494): 2.59e-165: 486: 73.57		EFNA1_HUMAN (11-162): 3.85e-69: 211: 43.59
+	Hs
		407416 K2C1_HUMAN (128-494): 2.59e-165: 486: 73.57		EFNA3_HUMAN (21-169): 8.49e-61: 191: 42.50
+	Hs
		914291 K2C73_HUMAN (3-560): 6.16e-99: 312: 53.41		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		407265 K2C6B_HUMAN (1-499): 1.28e-92: 296: 99.00		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		914240 KRT83_HUMAN (71-547): 1.79e-90: 288: 48.43		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		385252 K2C6A_HUMAN (1-499): 7.36e-88: 284: 98.40		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		914241 KRT85_HUMAN (1-528): 7.55e-89: 284: 47.16		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		566348 K2C5_HUMAN (3-479): 2.32e-86: 280: 77.43		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		914352 KRT82_HUMAN (41-560): 5.02e-85: 275: 48.08		EFNA4_HUMAN (1-185): 1.69e-86: 255: 100.00
+	Hs
		407252 K2C6B_HUMAN (1-499): 1.28e-92: 296: 99.00		EFNA1_HUMAN (11-162): 3.85e-69: 211: 43.59
+	Hs
		635245 K2C6C_HUMAN (1-499): 3.2e-92: 295: 100.00		EFNA1_HUMAN (11-162): 3.85e-69: 211: 43.59
+	Hs
		385238 K2C6A_HUMAN (1-499): 7.36e-88: 284: 98.40		EFNA1_HUMAN (11-162): 3.85e-69: 211: 43.59
+	Hs
		566332 K2C5_HUMAN (3-479): 2.32e-86: 280: 77.43		EFNA1_HUMAN (11-162): 3.85e-69: 211: 43.59
+	Hs
		407264 K2C6B_HUMAN (1-499): 1.28e-92: 296: 99.00		EFNA3_HUMAN (21-169): 8.49e-61: 191: 42.50
+	Hs
		876454 K2C6C_HUMAN (1-499): 3.2e-92: 295: 100.00		EFNA3_HUMAN (21-169): 8.49e-61: 191: 42.50
+	Hs
		385251 K2C6A_HUMAN (1-499): 7.36e-88: 284: 98.40		EFNA3_HUMAN (21-169): 8.49e-61: 191: 42.50
+	Hs
		566347 K2C5_HUMAN (3-479): 2.32e-86: 280: 77.43		EFNA3_HUMAN (21-169): 8.49e-61: 191: 42.50
+	Hs
		914199 K2C71_HUMAN (3-557): 7.59e-87: 280: 52.97		EFNA3_HUMAN (21-169): 8.49e-61: 191: 42.50