HitPredict

Interactor 1: EFNA1 (P20827)
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]
Gene: EFNA1

Interactor 2: K2C6C (P48668)
Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK-6C) (Cytokeratin-6E) (CK-6E) (Keratin K6h) (Keratin-6C) (K6C) (Type-II keratin Kb12)
Gene: KRT6C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23686814
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 564
+	Hs
		407390 EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00		K2C1_HUMAN (128-494): 2.59e-165: 486: 73.57
+	Hs
		407416 EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00		K2C1_HUMAN (128-494): 2.59e-165: 486: 73.57
+	Hs
		407417 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		K2C1_HUMAN (128-494): 2.59e-165: 486: 73.57
+	Hs
		407252 EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00		K2C6B_HUMAN (1-499): 1.28e-92: 296: 99.00
+	Hs
		385238 EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00		K2C6A_HUMAN (1-499): 7.36e-88: 284: 98.40
+	Hs
		566332 EFNA1_HUMAN (1-205): 2.56e-101: 293: 100.00		K2C5_HUMAN (3-479): 2.32e-86: 280: 77.43
+	Hs
		407264 EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00		K2C6B_HUMAN (1-499): 1.28e-92: 296: 99.00
+	Hs
		876454 EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00		K2C6C_HUMAN (1-499): 3.2e-92: 295: 100.00
+	Hs
		914291 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		K2C73_HUMAN (3-560): 6.16e-99: 312: 53.41
+	Hs
		385251 EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00		K2C6A_HUMAN (1-499): 7.36e-88: 284: 98.40
+	Hs
		566347 EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00		K2C5_HUMAN (3-479): 2.32e-86: 280: 77.43
+	Hs
		914199 EFNA3_HUMAN (14-187): 1.51e-67: 208: 40.00		K2C71_HUMAN (3-557): 7.59e-87: 280: 52.97
+	Hs
		407265 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		K2C6B_HUMAN (1-499): 1.28e-92: 296: 99.00
+	Hs
		876455 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		K2C6C_HUMAN (1-499): 3.2e-92: 295: 100.00
+	Hs
		914240 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		KRT83_HUMAN (71-547): 1.79e-90: 288: 48.43
+	Hs
		385252 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		K2C6A_HUMAN (1-499): 7.36e-88: 284: 98.40
+	Hs
		914241 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		KRT85_HUMAN (1-528): 7.55e-89: 284: 47.16
+	Hs
		566348 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		K2C5_HUMAN (3-479): 2.32e-86: 280: 77.43
+	Hs
		914352 EFNA4_HUMAN (4-170): 8.1e-61: 190: 39.88		KRT82_HUMAN (41-560): 5.02e-85: 275: 48.08